Home

User Panes

Ketoprofen, Diclofenac and Naproxen have shown to decrease reports of depression and anxiety by a factor of 2.32 and 2.86, 2.22 and 2.13, and 1.92 and 1.23 respectively, findings from a  recent population scale retrospective analysis.

7min read    

A recent research published in Public Health Nutrition Journal revealed a significant relationship between low 25(OH)D concentrations and pain conditions.

7min read    

As per a recent study conducted by Zhe Li and colleagues, unilateral percutaneous kyphoplasty (PKP) represents a reliable and safe therapy for osteoporotic vertebral compression fractures (OVCFs) with an intravertebral cleft (IVC). The study involved 309 patients, 266 females and 43 males who obtained PKP treatment from 2010 to 2016. Based on the pre-operative magnetic resonance imaging, the patients were categorized into two groups; OVCFs with IVC and OVCFs without IVC. The posterior wall height (PWH), kyphotic angle (KA) and anterior wall height (AWH) before, after the treatment and at final follow-up were assessed in both groups.

8min read    

A recent trial published in “Lasers in Medical Science” journal enlightens the role of laser irradiation in managing orthodontic pain during fixed appliance treatment if applied immediately. The pain during orthodontic surgeries is intense, especially for 2 to 4 days after fixed appliance treatment. Therefore, Isabela Parsekian Martins and colleagues assessed the effect of low-level laser therapy on dental pain by conducting a randomized, blinded clinical trial.

7min read    

Korean Scientists Bae SC and Lee YH carried out the Bayesian network meta-analysis in which they combined the direct and indirect evidence from various randomized controlled trials (RCTs) examining the safety and efficacy of biosimilar + MTX and infliximab + MTX and placebo + MTX (MTX group) in patients with active RA despite treatment with MTX.

7min read    
Key Take-Away:

A longitudinal interaction between pain interference and depression with the burden of headache in individuals with chronic tension type headache (CTTH) was found.

A tension-type headache (TTH) is the third most prevalent pain condition with an estimated prevalence of 42%. In 2010, the general costs for treatment of headache, most related to migraine and TTH, in Europe was €13.8 billion. 

J Headache Pain. 2017 Dec 28;18(1):119
29min read    
Key Take-Away:

The analysis discovers moderate – quality evidence regarding manipulation and mobilization therapies role in lessening pain and disability with complete safety.

Low back pain is counting among the diseases which cause most devastation in a person's life. About 23% of the population suffering from low back pain. Out of which, 11%–12% population exhibit disability due to severe pain. The management of low back pain involves various modalities; pharmacological as well as non-pharmacological. One section of doctors prefer pharmacological approaches like steroids, NSAIDs, neurotropic, opioid or surgery, While other choose non-pharmacological approaches as these associated with lesser adverse effects. 

Spine J. Author manuscript; available in PMC 2018 Jun 27
26min read    
Key Take-Away:

Both dynamic contrast-enhanced MRI (DCE-MRI) and RA MRI Score (RAMRIS) measures were equally sensitive to treatment effects with Infliximab.

With the technology advancements over the past decade, the treatment options for rheumatoid arthritis (RA) have expanded markedly. However, the acceptable duration for placebo control has also shortened, with rescue therapy typically offered within 14–16 weeks.

PLoS One. 2017 Dec 13; 12(12):e0187397
32min read    
Key Take-Away:

Dexmedetomidine-ketamine combination is a safe alternative for sedation during the cardiac catheterization procedure without the incidence of any hemodynamic or respiratory effects. However, it is associated with some delayed recovery. 

Management of children with congenital heart disease is challenging for anesthesiologists, especially during cardiac catheterization. 

Joshi VS, Kollu SS, Sharma RM. Ann Card Anaesth 2017;20:422-6
18min read    
Key Take-Away:

There is moderate-to high-quality evidence that anticonvulsants are ineffective for the treatment of low back pain or lumbar radicular pain. There is high-quality evidence that gabapentinoids have a higher risk of adverse events.

Globally, millions of people are suffered from low back pain (LBP) and become a major cause of disability than any other health complication. It is predicted that about 5% to 10% of patients with LBP have sciatica and followed by leg pain.

CMAJ. 2018 Jul 3;190(26):E786-93.
18min read    
Education

Sinusitis affects about 1 in 8 adults in the United States, resulting in over 30 million annual diagnoses.

American Academy of Otolaryngology-Head and Neck Surgery Foundation
15 min read    
Education

Chronic pain can be a serious consequence of surviving cancer. The prevalence of pain in cancer survivors has been reported to be as high as 40%.

American Society of Clinical Oncology
10 min read    
Education

Neuropathic pain is defined as the pain initiated or caused by a primary lesion, dysfunction, or transitory perturbation of peripheral or central nervous system.

Western Australian Therapeutic Advisory Group
2min read    
Education

Transitional care, as defined by the Society for Adolescent Medicine refers to the purposeful, planned movement of adolescents and young adults with chronic physical and medical conditions from chi

Ann Rheum Dis 2016;0:1–8
4min read    
Education

As per the World Health Organization (WHO), osteoporosis refers to a progressive systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of the bone tissues, w

Arch Osteoporos. 2017; 12(1): 43.
2min read    
July 19, 2018

Ketoprofen, Diclofenac and Naproxen have shown to decrease reports of depression and anxiety by a factor of 2.32 and 2.86, 2.22 and 2.13, and 1.92 and 1.23 respectively, findings from a  recent population scale retrospective analysis.

Key Take-Away:

A longitudinal interaction between pain interference and depression with the burden of headache in individuals with chronic tension type headache (CTTH) was found.

A tension-type headache (TTH) is the third most prevalent pain condition with an estimated prevalence of 42%.

J Headache Pain. 2017 Dec 28;18(1):119
29min read    
Education

Sinusitis affects about 1 in 8 adults in the United States, resulting in over 30 million annual diagnoses. Sinusitis is the fifth most common diagnosis in the world; more than 1 in 5 antibiotics prescribed in adults are for sinusitis. Irrespective of the high incidence and economic burden of sinusitis, significant practice dissimilarities exist through and within the numerous disciplines involved in managing the condition. The guideline is applicable for patients aged 18 years and above with a clinical diagnosis of uncomplicated rhinosinusitis.

American Academy of Otolaryngology-Head and Neck Surgery Foundation
15 min read