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According to a recent review study published in the Current Pain and Headache Reports journal, the behavioral pattern of a person is significantly linked with episodic migraine attacks and related disability. An episodic migraine involves 0 to 14 migraine attacks per month. How an individual behavior triggers or intensifies an episodic migraine is still under review.

6min read    
Pain Management

As per recent research conducted in the Department of Anesthesiology and Intensive Care Medicine, Lovran, Croatia, the postoperative regional analgesia helps to maintain cell-mediated immunity and perforin expression in peripheral blood lymphocytes in patients after Total knee replacement (TKR).

8min read    
Pain Management

A recent study has found that abatacept can reduce synovial regulatory T-cell expression (Treg) in patients with psoriatic arthritis (PsA) and thus, can be considered as an effective treatment option for joint pain.

9min read    
Pain Management

A new monoclonal antibody, Erenumab was found efficacious in reducing migraine attacks and medication overuse. A migraine is counted as the 3rd most prevalent disease throughout the world. Many people suffered from a headache are used to take more and more painkillers. The problem of medication overuse may soon cease with the help of an antibody; an antibody reduces the count of migraine attacks.

8min read    
Pain Management

Anti-retroviral therapy has led to a significant decline in mortality of individuals infected with human immunodeficiency virus (HIV). According to latest HIV treatment guidelines, antiretroviral treatment (ART) should be initiated at the time of diagnosis. A recent study has revealed that early ART can cause more significant bone loss compared with deferring ART.
This study followed 399 participants (195 received immediate ART and 204 deferred ART) for an average of 2.2 years.
The study determined an adverse effect on bone density in patients on immediate ART. But the overall benefits of ART for preventing HIV transmission and adverse health outcomes outweighs this adverse effects.

6min read    
Clinical Research
Key Take-Away:

Thiazide diuretic may decrease the risk of fracture, indicating the protective effect of this class in clinical practice.

Osteoporosis is a major chronic condition worldwide, and the major health issue in the USA especially in the aging population. About 300,000 people aged 65 and older are hospitalized each year due to hip fracture, a situation which often leads to decreased quality of life.

Osteoporosis Int. 2018 Mar 25
20min read    
Clinical Research
Key Take-Away:

In middle-aged people with mild radiographic osteoarthritis (OA), structural features changes do occur  a little over a year, irrespective of weight patients loss status.

Osteoarthritis (OA) is a principal cause of disability and a more massive public health problem in the United States.

Osteoarthritis and Cartilage
20min read    
Clinical Research
Key Take-Away:

Home-based, telephone-delivered Cognitive-Behavioral Therapy (CBT) and Supportive Care (SC) treatments did not significantly differ in their benefits for back pain severity and disability, and may warrant further research for applications to hospital settings.

Over the past decade, there is a drastically hype in the prevalence of chronic back pain (CBP) in the US population, advising a need for more treatment resources.

The Clinical Journal of Pain 2018;34(4): 322–327
22min read    
Systematic Reviews
Key Take-Away:

Intra-articular administration of dexmedetomidine (DEX) improved pain outcomes in the early postoperative period after knee arthroscopy

Arthroscopic knee surgery is a surgical procedure that can diagnose and treat problems in the knee joint. Patients with knee pain are managed on a day-case basis; therefore, appropriate postoperative pain relief is critical to facilitate patient discharge and early recovery.

Sci Rep. 2018 Mar 6;8(1):4089.
17min read    
Abstracts
Key Take-Away:

The problem of a migraine is considered among the ten most disabling disorders that may arise in any age group. Various medications are available for the prevention and treatment of a migraine in pediatric patients. This study enlightens the efficacy of an approved anticonvulsant drug topiramate among adolescents generating mixed results.

Based on the success of treatment, various medications are prescribed to prevent pediatric migraines. Topiramate, the drug approved for migraine prevention in children as young as 12 years of age. 

8min read    
Education
Smart Guidelines

Sinusitis affects about 1 in 8 adults in the United States, resulting in over 30 million annual diagnoses.

American Academy of Otolaryngology-Head and Neck Surgery Foundation
15 min read    
Education
Smart Guidelines

Chronic pain can be a serious consequence of surviving cancer. The prevalence of pain in cancer survivors has been reported to be as high as 40%.

American Society of Clinical Oncology
10 min read    
Education
Smart Guidelines

Neuropathic pain is defined as the pain initiated or caused by a primary lesion, dysfunction, or transitory perturbation of peripheral or central nervous system.

Western Australian Therapeutic Advisory Group
2min read    
Education
Smart Guidelines

Transitional care, as defined by the Society for Adolescent Medicine refers to the purposeful, planned movement of adolescents and young adults with chronic physical and medical conditions from chi

Ann Rheum Dis 2016;0:1–8
4min read    
Education
Smart Guidelines

As per the World Health Organization (WHO), osteoporosis refers to a progressive systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of the bone tissues, w

Arch Osteoporos. 2017; 12(1): 43.
2min read    
Pain Management
September 20, 2018

According to a recent review study published in the Current Pain and Headache Reports journal, the behavioral pattern of a person is significantly linked with episodic migraine attacks and related disability. An episodic migraine involves 0 to 14 migraine attacks per month. How an individual behavior triggers or intensifies an episodic migraine is still under review.

Clinical Research
Key Take-Away:

Thiazide diuretic may decrease the risk of fracture, indicating the protective effect of this class in clinical practice.

Osteoporosis is a major chronic condition worldwide, and the major health issue in the USA especially in the aging population. About 300,000 people aged 65 and older are hospitalized each year due to hip fracture, a situation which often leads to decreased quality of life.

Osteoporosis Int. 2018 Mar 25
20min read    
Education
Smart Guidelines

Sinusitis affects about 1 in 8 adults in the United States, resulting in over 30 million annual diagnoses. Sinusitis is the fifth most common diagnosis in the world; more than 1 in 5 antibiotics prescribed in adults are for sinusitis.

American Academy of Otolaryngology-Head and Neck Surgery Foundation
15 min read