In the report of an analysis conducted by the investigators of the Montefiore Headache Center, Albert Einstein College of Medicine, New York, the need for specific protocols and guidelines appeared for the management of migraine during pregnancy. One of the common problems arise among pregnant women is the migraine, and it is difficult to treat this issue due to fears of medication teratogenicity and lack of evidence in this population.
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A sigh of relief for migraineurs, the US FDA has recently approved Fremanezumab preventive treatment of migraine among adults. Migraine is one of the primary cause of disability that causes a severe headache with photophobia, phonophobia, nausea and vomiting.
6min read
A recent pilot study presents a simple electrophysiological marker that can potentially improve the prediction of migraine attacks. The problem of migraine led to considerable discomfort and decreased functioning for days at a time, involving the pre-ictal and post-ictal periods.
7min read
In recent research undertaken by the University of Campania "Luigi Vanvitelli", post-menopausal females with vertebral fractures showed significant improved HRQoL and decreased pain-related disability with Denosumab administration. Denosumab is a type of monoclonal antibody that hinders the osteoclast-mediated bone resorption by neutralizing the receptor activator of nuclear factor kappa-Β ligand (RANKL).
8min read
According to a recent narrative review published in the BMC Musculoskeletal Disorders, osteoarthritis of the elbow can be effectively and safely treated with the open and arthroscopic debridement procedures.
Elbow OA considered as one of the major disabling infirmity due to severe pain and loss of function. Open and arthroscopic debridement is the favoured approach to manage this critical condition, but no consent is available to define which therapy is befitted to which class of patient or stage of the elbow OA.
7min read
Key Take-Away:
This study elucidates a longitudinal relationship between varus knee thrust noticed during walking and knee pain. The use of biomechanical interventions to mitigate thrust in the prevention of new and worsening of pain can be justified by using the longitudinal relationship between knee thrust and WOMAC pain.
Introduction:
To investigate two year association of varus knee thrust perceived during walking with odds of worsening WOMAC knee pain in elderly with or at risk of OA.
7min read
Key Take-Away:
Adequate use of analgesics is integral during pregnancy. There is limited evidence in previous studies that have focused on drug utilization in pregnant women suffering from migraine. In this study, patterns of analgesic use in pregnant women has been predicted and it has been suggested that migraine and demographic characteristics of patients affects the use of analgesia.
Introduction:
To define patterns of analgesic use within a sample of Norwegian pregnant females on the basis of their migraine history and to recognise predictors for analgesic use amongst these females.
7min read
Key Take-Away:
Nephrolithiasis is a painful condition in which solid material stones get deposited in the kidney. There are a few studies in history that explain the association and risk of nephrolithiasis in gout patients. In this study, the incidence rate and risk factors of nephrolithiasis have been determined in gout patients, and various demographic characteristics of patients like age and sex were found to increase the risk of NL in patients with gout.
Introduction:
Nephrolithiasis (NL) is comprehended to be correlated with gout; but, the comparative studies on risk and risk factors for NL in gout were minimum. This analysis evaluated (a) overall rate of NL in gout (cases) and general population controls; (b) risk and risk factors for first-time NL in cases and controls independently.
8min read
Key Take-Away:
Friedman BW et al. elucidated that Greater Occipital Nerve Blocks (GONB) might be an effective treatment for ED patients with an acute migraine, suffering from a moderate or a severe headache after the application of intravenous metoclopramide. But, this investigation was discontinued before achieving a priori sample size due to the slow enrollment.
Introduction:
It is believed that Greater occipital nerve block (GONB) is an effective treatment for acute migraine, but there has been no randomized efficacy data published for the same. It was hypothesized that bilateral GONB with bupivacaine may lead to greater rates of headache freedom than a sham injection among emergency department (ED) patients who described the persistence of a moderate or severe headache despite standard treatment with i.v. Metoclopramide.
9min read
Key Take-Away:
Abatacept is costimulation modulator used for the management of RA. In this study, the MRI of bilateral hands affirmed that Abatacept reduced synovitis and osteitis scores among RA patients and did not worsen erosion and JSN scores, but erosion started to repair in 10% of patients.
Introduction:
To investigate the efficacy of Abatacept among patients with rheumatoid arthritis (RA) applying magnetic resonance imaging (MRI) of bilateral hands.
7min read
Education
Smart Guidelines
Pain is the leading cause of suffering, disability and medical care worldwide.
10 min read
Education
Presentations
Arthritis encompasses more than 100 different arthritic conditions which are a chronic, painful, and debilitating group of diseases.
15 min read
Education
Presentations
Rheumatoid arthritis (RA) is a chronic inflammatory disorder with an estimated prevalence of 0.5-1% of the population worldwide; it is also reported that women are more affected than men are. [1].
15 min read
Education
Presentations
Vitamins are organic compounds essential for normal physiological functions.
15 min read
Education
Presentations
The World Health Organization (WHO) describes the rational use of medicines as, “patients receive medications appropriate to their clinical needs, in doses that meet their own individual requiremen
5 min read
May 24, 2019
In the report of an analysis conducted by the investigators of the Montefiore Headache Center, Albert Einstein College of Medicine, New York, the need for specific protocols and guidelines appeared for the management of migraine during pregnancy. One of the common problems arise among pregnant women is the migraine, and it is difficult to treat this issue due to fears of medication teratogenicity and lack of evidence in this population.
Key Take-Away:
This study elucidates a longitudinal relationship between varus knee thrust noticed during walking and knee pain. The use of biomechanical interventions to mitigate thrust in the prevention of new and worsening of pain can be justified by using the longitudinal relationship between knee thrust and WOMAC pain.
Introduction:
To investigate two year association of varus knee thrust perceived during walking with odds of worsening WOMAC knee pain in elderly with or at risk of OA.
7min read
Education
Smart Guidelines
Pain is the leading cause of suffering, disability and medical care worldwide. Pain associated with chronic diseases are not life-threatening, but people continue to live with this pain in developed and developing countries affecting their overall quality of life.
10 min read