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Taking NSAIDs after 60? Study warns of increased G...
A large hospital-based study from Beijing has identified significant risk factors associated with nonsteroidal anti-inflammatory drug (NSAID)-ind...
Low-dose aspirin raises gastric and duodenal ulcer...
A large population-based analysis of over 220,000 volunteers has revealed that low-dose aspirin initiation is connected with increased risk of ga...
2 min
Tegoprazan emerges as fast-acting alternative to P...
A large study has positioned tegoprazan, a potassium-competitive acid blocker (PCAB), as a next-generation therapy for gastroesophageal reflux di...
2 min
Global PPI use hits 25%: Study flags rising long-t...
A large-scale systematic review assessing global trends in proton pump inhibitor (PPI) use has revealed that these acid-suppressing drugs are use...
2 min
Updated clinical guidance highlights optimal treat...
Helicobacter pylori (H. pylori) infection remains one of the most common chronic bacterial infections worldwide and is a major contributor to dys...
1 min
Tradipitant
Tradipitant is a centrally acting antiemetic approved by the Food and Drug Administration (FDA) on 30 December 2025 for the prevention of motion...
5 min
High-dose vs. conventional therapy for H. pylori e...
Optimizing Helicobacter pylori (H. pylori) eradication therapy is fundamental in the era of rising antibiotic resistance.
3 min
Multi-strain probiotics as nutritional therapy for...
Chronic constipation is a common gastrointestinal disorder among middle-aged and older adults, often linked with reduced quality of life and limi...
3 min
Omeprazole–domperidone combination delivers signif...
Acid peptic disease (APD) continues to impose a considerable gastrointestinal burden on patients with Type 2 diabetes mellitus (T2DM), with sympt...
1 min
Fidaxomicin
Fidaxomicin is a novel macrocyclic macrolide antibiotic and the first member of a new class of antimicrobial agents.
6 min
Prevention of NSAID-induced peptic ulcers in high-risk patients:...
Proton pump inhibitor monotherapy remains a highly evidence-supported strategy for preventing NSAID-induced peptic ulcer recurrence and gastroint...
Tegoprazan offers rapid and sustained acid suppression in GERD
Tegoprazan demonstrates rapid acid suppression and superior nocturnal symptom control, strengthening its potential as an effective alternative to...
MEN1-associated Zollinger-Ellison syndrome: New evidence supports...
Surgical intervention shows promise in selected patients with MEN1-associated Zollinger-Ellison syndrome, with new evidence highlighting improved...
Magaldrate quadruple therapy matches bismuth in H. pylori eradica...
Magaldrate granules combined with rabeprazole, amoxicillin, and clarithromycin achieve H. pylori eradication rates comparable to standard bismuth...
Lactobacillus reuteri as an adjunct to triple therapy for H. pylo...
Supplementing standard triple therapy with Lactobacillus reuteri significantly improves Helicobacter pylori eradication rates and minimizes commo...
New questionnaire uncovers gaps in adolescent IBD transition care
The validated Mind the Gap questionnaire identifies essential environmental enhancements required to optimize the transition from paediatric to a...
Dual therapy emerges as a simpler first-line strategy for H. pylo...
Dual therapy with vonoprazan and amoxicillin shows comparable eradication efficacy, fewer adverse events, and better treatment compliance than qu...
Can targeted drug delivery overcome gastrointestinal barriers?
Advanced drug delivery systems are being designed to overcome gastrointestinal barriers and deliver medicines more precisely to diseased sites, p...
Benefits of omeprazole for gastrooesophageal reflux in obstructiv...
Treating gastrooesophageal reflux with prolonged omeprazole (20 mg) therapy progressively reduces the frequency of obstructive sleep apnoea attac...
Semaglutide and tirzepatide redefine treatment goals in MASLD
Semaglutide and tirzepatide reshape the treatment landscape of MASLD by coupling histologic liver improvement with proven cardiometabolic protect...
New research shows dual therapy rivals bismuth quadruple regimen...
A comprehensive meta-analysis found that 14-day tegoprazan–amoxicillin dual therapy achieved H. pylori eradication rates comparable to BQT,...
Linerixibat, an ileal bile acid transporter (IBAT) inhibitor, is approved by the Food and Drug Administration (FDA) in 2026 for cholestatic pruri...
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