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Updated clinical guidance highlights optimal treat...
Helicobacter pylori (H. pylori) infection remains one of the most common chronic bacterial infections worldwide and is a major contributor to dys...
Multi-strain probiotics as nutritional therapy for...
Chronic constipation is a common gastrointestinal disorder among middle-aged and older adults, often linked with reduced quality of life and limi...
3 min
Helicobacter pylori as a Reversible Cause of Treat...
Fidaxomicin
Fidaxomicin is a novel macrocyclic macrolide antibiotic and the first member of a new class of antimicrobial agents.
6 min
Omeprazole–domperidone combination delivers signif...
Acid peptic disease (APD) continues to impose a considerable gastrointestinal burden on patients with Type 2 diabetes mellitus (T2DM), with sympt...
1 min
New German S1 guideline updates diagnosis and trea...
Functional dyspepsia (FD), a common disorder of gut–brain interaction (DGBI), remains a common yet clinically challenging disorder because...
1 min
Why some GERD patients feel more heartburn than ot...
The relationship between esophageal acid exposure and symptom severity in gastroesophageal reflux disease (GERD) is often complex, with high leve...
1 min
Nitazoxanide-based regimens outperform standard tr...
A novel systematic review and meta-analysis of randomized controlled trials suggests that nitazoxanide (NTZ)-based triple therapy may offer super...
2 min
Persistent Belching in Functional Dyspepsia Succes...
Management strategies for small bowel obstruction...
Small bowel obstruction and no prior abdominal surgery (NPA-SBO) presents a complex clinical condition.
2 min
Acotiamide for esophagogastric junction outflow obstruction: Phas...
Acotiamide significantly improves lower esophageal sphincter relaxation in patients with esophagogastric junction outflow obstruction, with sympt...
Understanding gastrointestinal anxiety in inflammatory bowel dise...
Gastrointestinal-specific anxiety in inflammatory bowel disease is driven primarily by systemic psychological distress rather than local inflamma...
Nocturnal GERD and sleep disruption: Systematic review highlights...
Proton pump inhibitor (PPI) therapy reduces nighttime heartburn and gastroesophageal reflux disease (GERD)–related sleep disturbances witho...
OSA linked to higher risk of GERD and esophageal complications
Patients with obstructive sleep apnea experience significantly higher GERD incidence and greater risk of esophageal complications.
Which H. pylori treatment works best? Meta-analysis reveals effic...
Ten-day and PCAB-based regimens achieve relatively higher H. pylori eradication rates, whereas sequential and multi-antibiotic regimens are assoc...
Vonoprazan vs. PPIs: Which acid blocker comes out ahead?
Vonoprazan emerges as a superior therapeutic alternative to traditional proton pump inhibitors for both Helicobacter pylori eradication and the m...
Second Asian consensus on functional dyspepsia: What’s new in dia...
Updated 2025 consensus guidance refines functional dyspepsia management with new mechanistic insights and personalized care recommendations.
Prevention of NSAID-induced peptic ulcers in high-risk patients:...
Proton pump inhibitor monotherapy remains a highly evidence-supported strategy for preventing NSAID-induced peptic ulcer recurrence and gastroint...
Tegoprazan offers rapid and sustained acid suppression in GERD
Tegoprazan demonstrates rapid acid suppression and superior nocturnal symptom control, strengthening its potential as an effective alternative to...
MEN1-associated Zollinger-Ellison syndrome: New evidence supports...
Surgical intervention shows promise in selected patients with MEN1-associated Zollinger-Ellison syndrome, with new evidence highlighting improved...
Magaldrate quadruple therapy matches bismuth in H. pylori eradica...
Magaldrate granules combined with rabeprazole, amoxicillin, and clarithromycin achieve H. pylori eradication rates comparable to standard bismuth...
Lactobacillus reuteri as an adjunct to triple therapy for H. pylo...
Supplementing standard triple therapy with Lactobacillus reuteri significantly improves Helicobacter pylori eradication rates and minimizes commo...
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