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Loxoprofen sodium cataplasm outperforms flurbiprof...
A multicenter randomized controlled trial has shown that loxoprofen sodium cataplasm (LSC) may deliver greater short-term symptom relief than flu...
Zaltoprofen shows noninferior potency to loxoprofe...
A multicenter, placebo-controlled, randomized clinical trial evaluated whether a single dose of zaltoprofen 160 mg could deliver fever and pain r...
2 min
Loxoprofen provides rapid lumbar pain relief in el...
A large multicentre study involving more than 4,000 elderly patients found that loxoprofen sodium offered meaningful relief from lumbar pain whil...
2 min
Imrecoxib vs. celecoxib: New evidence supports non...
Evidence pooled from randomized controlled trials (RCTs) indicates that imrecoxib provides pain relief and anti-inflammatory effects comparable t...
1 min
Tegileridine vs. oliceridine vs. morphine: Compari...
Tegileridine, a novel biased µ-opioid receptor agonist, is gaining attention in moderate-to-severe pain management, but direct comparisons...
1 min
Post-IVF pain flares common in endometriosis, larg...
A large international survey indicates that in vitro fertilization (IVF) may be associated with worsening pelvic pain symptoms in a substantial p...
1 min
PRP outperforms corticosteroids for long-term pain...
Lateral epicondylitis, widely known as tennis elbow, is one of the key causes of elbow pain and upper-limb disability, influencing predominantly...
2 min
Probiotic supplementation offers new hope for wome...
Despite affecting a large proportion of reproductive-aged women, primary dysmenorrhea continues to be tackled predominantly with analgesics and h...
1 min
Efficacy of loxoprofen sodium + sodium hyaluronate...
This study investigated whether loxoprofen sodium + sodium hyaluronate offers superior therapeutic benefit in osteoarthritis (OA) and also assess...
3 min
Structured exercise eases foot pain and improves m...
According to a new systematic review and meta-analysis, structured, supervised exercise programs can considerably reduce foot pain and improve mo...
1 min
Efficacy of pregabalin + thioctic acid in painful diabetic periph...
Combining low-dose pregabalin (80 mg) with thioctic acid (400 mg) twice daily provides non-inferior pain relief to high-dose pregabalin (150 mg)...
High insulin sensitivity linked to 52.4% drop in chronic pain ris...
Higher insulin sensitivity, measured by the estimated glucose disposal rate, independently predicts a drastically lower risk of chronic pain, par...
Hyaluronic acid injections in knee osteoarthritis: Expert consens...
Expert consensus supports intra-articular hyaluronic acid as a patient-centered treatment option for knee osteoarthritis, particularly outside ac...
Role of preemptive intravenous ibuprofen in laparoscopic cholecys...
A single 400-mg preemptive intravenous dose of ibuprofen improves postoperative analgesia, prolongs time to first rescue analgesia, and reduces t...
Nortriptyline-based strategies for episodic migraine prevention
Combination preventive therapy delivers a greater reduction in monthly headache days and better treatment adherence than nortriptyline monotherap...
Efficacy of mesotherapy vs. oral combination therapy in acute and...
Intradermal mesotherapy significantly reduces pain and neck-related disability, with outcomes comparable to oral meloxicam + thiocolchicoside ove...
Transpedal genicular artery embolization eases chronic knee osteo...
In patients suffering from chronic knee osteoarthritis, transpedal genicular artery embolization shows sustained 6-month improvements in pain and...
Novel fusion protein LEVI-04 effectively reduces knee OA pain
LEVI-04, a new neurotrophin-3 inhibitor, is beneficial to improve pain and physical function in knee osteoarthritis while maintaining a favorable...
Ibuprofen vs. acetaminophen in children: New evidence on safety f...
Ibuprofen and acetaminophen show comparable short-term safety in children with acute pain.
Ketorolac offers effective nonopioid analgesia for acute pain in...
Ketorolac provides analgesia comparable to opioids across multiple acute pain conditions in adults presenting to the emergency department.
Headache relief or trigger? The complex role of caffeine!
Caffeine has a dual role in headaches, providing analgesic effects while also acting as a potential trigger. Its effects vary with dose, intake p...
Nimesulide–paracetamol for acute painful conditions: A real-world...
Nimesulide–paracetamol combination therapy provides substantial pain relief across diverse acute painful conditions.
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