Categories
Change Password!
Reset Password!
This randomized controlled trial set out to compare the effectiveness of intravenous ibuprofen and ketorolac for perioperative pain relief in individuals with obesity undergoing bariatric surgery.
This randomized controlled trial set out to compare the effectiveness of intravenous ibuprofen and ketorolac for perioperative pain relief in individuals with obesity undergoing bariatric surgery.
Adults scheduled for bariatric surgery were randomly assigned to receive intravenous ibuprofen or ketorolac every 8 hours. All volunteers were also administered 1 g of intravenous paracetamol every 6 hours. Fentanyl was used to manage inadequate intraoperative pain, while postoperative pain was addressed with nalbuphine boluses as required.
The key outcome measured was static pain intensity via the visual analog scale (VAS) at 30 minutes post-surgery. Secondary outcomes encompassed patient satisfaction, static and dynamic VAS scores postoperatively, opioid consumption during and after surgery, and occurrence of postoperative nausea and vomiting (PONV).
A total of 53 patients were analyzed in each treatment group. At 30 minutes post-op, the median VAS score was markedly lower in the ketorolac group (3 [3, 6]) when compared to the ibuprofen group (7 [4, 8]) (P < 0.001). Ketorolac also outperformed ibuprofen in both static and dynamic pain scores up to 6 hours after surgery. Those who received ketorolac required fewer intra- and postoperative opioids and experienced less PONV. Furthermore, satisfaction scores were higher among those in the ketorolac group.
Among patients with obesity undergoing bariatric surgery, intravenous ketorolac yielded superior perioperative analgesia, lowered opioid requirements, and minimized the incidence of nausea and vomiting post-surgery when compared to ibuprofen. It also led to greater overall patient satisfaction.
Obesity Surgery
Intravenous Ibuprofen Versus Ketorolac for Perioperative Pain Control in Patients with Morbid Obesity Undergoing Bariatric Surgery: A Randomized Controlled Trial
Sarah Amin et al.
Comments (0)