As compared to the Intra-articular (IA)-hyaluronic acid and IA-corticosteroids, IA Platelet-rich plasma provides the better outcomes for symptomatic early stages of knee osteoarthritis, results of a recent study conducted by the investigators of Jining First People's Hospital and Jinan University. Knee osteoarthritis (KOA) is a degenerative joint condition with severe pain and disability for which no curative therapy is present.
As per the findings of a recently published paper in BMC Musculoskeletal Disorders journal, the fish intake solely not but its association with smoking linked to the risk of rheumatoid arthritis. Attempts are proceeding to identify risk factors for rheumatoid arthritis (RA). Where smoking is an essential risk factor for RA, many individuals who never smoked also develop RA, this indicates the involvement of other factors such as diet and obesity as well.
The Hospital for Special Surgery, New York, presents a report according to which the chances of revision and conversion are higher among people who received Patellofemoral arthroplasty (PFA) than total knee arthroplasty (TKA). To treat the last stage, isolated patellofemoral arthritis (PFOA), TKA and PFA are the accepted therapies but with a different rate of re-operations and complications.
The β-D-mannuronic acid as a new, highly safe and efficient drug in the treatment of rheumatoid arthritis (RA) as elucidated from a multinational, phase III clinical study published in 'Inflammopharmacology' Earlier phase I/II study has described that the oral administration of drug- β-D-mannuronic acid (M2000) showed a significant therapeutic effect in RA patients. The safety and efficacy of this drug in RA patients have been evaluated in this phase III clinical trial.
Bisphosphonate discontinuation might be effective for women who do not have low hip BMD following 3–5 years of initial treatment, on the other hand, women who have low hip BMD may benefit from treatment continuation revealed in a study published in Osteoporosis International. S. Nayak and S. L. Greenspan executed a systematic review and meta-analysis studying the effect of drug holidays or drug discontinuation on BMD and fracture risk.
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