Non-operative management of uncomplicated acute appendicitis during pregnancy provides similar outcomes to surgery, indicating a shift in clinical practice towards less invasive options.
In a population-based study led by Marco Ceresoli et al., non-operative management for uncomplicated acute appendicitis during pregnancy resulted in comparable perinatal outcomes to surgical intervention. The aim was to investigate the management protocols and outcomes of acute appendicitis during gestation.
This research utilized the computerized healthcare utilization database of Lombardy, analyzing data from 1,231,040 deliveries to identify cases of pregnancy-related acute appendicitis. The study examined treatment approaches, maternal outcomes, and perinatal outcomes. Acute appendicitis in expectant mothers was found in just 0.03% of the deliveries, with 74.49% of these cases deemed as uncomplicated. Among the uncomplicated cases, 38.46% were tackled conservatively without surgery.
No vital differences were noted in perinatal outcomes between those treated non-operatively and those who underwent surgery. One of the key trends was a noticeable decline in the number of surgical interventions over the study period, with a P-value of 0.0477, reflecting a growing preference for conservative care aimed at minimizing the risks linked with surgery during pregnancy.
To sum up, non-operative management appears to be a viable option for pregnant women with uncomplicated appendicitis, offering comparable outcomes to surgery while potentially avoiding surgical complications and facilitating faster recovery. Additional studies are warranted to substantiate these findings and refine clinical practice guidelines.
Archives of Gynecology and Obstetrics
Operative and non-operative management of acute appendicitis during pregnancy: a population-based study
Marco Ceresoli et al.
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