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PCOS patients with blood type O exhibit heavier menstrual bleeding and a more favorable endocrine status when compared to those with non-O blood types.
A cross-sectional survey exploring the link between ABO blood groups and polycystic ovary syndrome (PCOS) has uncovered a possible connection between blood type and menstrual characteristics in the affected females.
Shuhan Yang and other researchers investigated 445 women—312 diagnosed with PCOS and 133 healthy controls. Participants provided information on their menstrual patterns and ABO blood type via questionnaires. Additionally, their blood lipid levels and hormone profiles were estimated. The study aimed to analyze whether ABO blood type is linked to menstrual regularity, menstrual bleeding volume, and metabolic or hormonal markers in PCOS patients.
The findings revealed a statistically significant association between ABO blood type distribution and menstrual bleeding level among PCOS patients (P = 0.036). Women with PCOS and blood type O showed considerably different values in several parameters when compared to non-O blood types:
They also exhibited a greater tendency towards heavier menstrual bleeding. The study concludes that ABO blood type—especially type O—appears to be associated with specific reproductive and metabolic features in PCOS.
BMC Endocrine Disorders
Menstrual disorder is associated with blood type in PCOS patients: evidence from a cross-sectional survey
Shuhan Yang et al.
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