Study links LH/FSH ratio with postural abnormalities in PCOS :- Medznat
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Biomechanical changes in PCOS correlate with LH/FSH ratio

PCOS PCOS
PCOS PCOS

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Women with PCOS exhibit markedly greater pelvic tilt and lumbar lordosis, strongly correlated with an elevated LH/FSH ratio.

A new case–control study has revealed that women with polycystic ovarian syndrome (PCOS) have substantially higher pelvic inclination and exaggerated lumbar curvature compared to women without the condition, and these postural changes are strongly connected with an elevated luteinizing hormone to follicle-stimulating hormone (LH/FSH) ratio.

PCOS, a widespread endocrine disorder, disrupts the normal balance between key hormones [luteinizing hormone (LH) and follicle-stimulating hormone (FSH)], often inverting their ratio. This altered hormonal profile, along with chronic low-grade inflammation commonly seen in PCOS, is known to decrease muscle strength and mass—particularly in the lumbopelvic region—leading to postural deformities and spinal misalignment.

The study involved 95 nulliparous women aged 25–35 years with a body mass index (BMI) between 25 and 29.9 kg/m². Of these, 52 women with PCOS were classified into the study group, while 43 healthy individuals formed the control group. The pelvic and lumbar angles were assessed using a pelvic inclinometer and a spinal inclinometer, respectively, while blood samples were drawn on the 3rd day of the menstrual cycle to determine LH and FSH levels.

Results showed that women with PCOS had a markedly increased pelvic tilt and deeper lumbar curve when compared to controls. Notably, the LH/FSH ratio illustrated a robust correlation with both the pelvic inclination angle and lumbar curvature. These findings suggest that hormonal dysregulation in PCOS may have a direct biomechanical impact on posture. The study highlights the need for clinicians to consider musculoskeletal assessment and postural care in the holistic management of PCOS.

Source:

Scientific Reports

Article:

Biomechanical changes in females with polycystic ovarian syndrome: a case–control study

Authors:

Eman E. Kamal et al.

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