High-intensity laser therapy (HILT) along with exercise programs emerges as a beneficial therapeutic strategy for knee osteoarthritis (KOA) management, an analysis by the Department of Sports Medicine, School of Medicine, Iran University of Medical Sciences. KOA is considered as a prevalent joint disorder that leads to severe pain and functional disability.
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Headache associated with temporomandibular disorders ((TMDH) found to have a significant relationship with elevated TMD pain intensity, increased number of self‐reported bodily pain conditions and the greater number of painful sites in the neck and head zones according to research published in the Journal of head and face pain. The International Classification of Headache Disorders 3rd edition (ICHD-3) designated TMDH as a secondary headache.
7min read
As per a recent randomized, double-blinded, placebo-controlled parallel analysis led by P. Gazerani and colleagues, the Vitamin-D3 supplementation found to reduce migraine attacks in the migraine patients. Vitamin D shows a substantial role in managing various kinds of pain conditions.
8min read
As per a recent study published in the Journal, Electromagnetic Biology and Medicine highlights the significant role of electromagnetic transduction therapy (EMTT) combined with extracorporeal shock wave therapy (ESWT) to reduced pain and improve function than ESWT with sham-EMTT among the patients with Rotator cuff (RC) tendinopathy. RC tendinopathy is the primary reason behind having shoulder pain.
6min read
According to a recent analysis by Tomohiko Yoshida and colleagues, the latest formulation of Adalimumab significantly reduces the RA burden, enhance the treatment's adherence quality, less pain during needle insertion and improves the treatment outcomes. Adalimumab is a TNF-alpha blocker delivered via subcutaneous injection. However, the drug is associated with the risk of serious infections and pain at the injection site.
6min read
Key Take-Away:
The results of the study conclude that both LMA and LTS-D are suitable and useful for airway treatment in patients breathing spontaneously during general anaesthesia for minor surgery of short duration.
The laryngeal mask airway LMA and laryngealube suction-disposable (LTS-D) is the second generation single-use supraglottic airway devices (SADs) with gastric access that are used for management of airway during general anaesthesia in spontaneously and mechanically ventilated patients.
Somri M et al. J Anaesthesiol Clin Pharmacol 2018;34:182-7
12min read
Key Take-Away:
The results of this study indicate the use of the unloading knee brace in combination with usual care as a safe and superior therapy in relieving global pain and improving motion as compared to routine care.
Knee osteoarthritis (OA) refers to a common disabling disorder that leads to considerable pain, immobility, functional impairment and reduced quality of life. It becomes prevalent as the age of the population increases.
Philippe Thoumie et al. Scientific Reports. (2018) 8:10519
15min read
Key Take-Away:
The study concluded that the calcitonin gene-related peptide provoke cluster headache attacks in active-phase episodic cluster headache and chronic cluster headache but not in remission-phase episodic cluster headache. These results suggest anti-CGRP drugs may be useful in cluster headache management.
Cluster headache is a chronic headache disorder with a prevalence of 0.5 to 1.0 out of the population of 1000. Cluster headache attacks are characterised by prominent ipsilateral cephalic autonomic symptoms (CAS), such as tearing, conjunctival redness, rhinorrhea or nasal congestion, ptosis, as well as the sense of agitation or restlessness. Most of the patients experiencing episodic cluster headache with month-long attack periods separated by remission periods. The remaining 10% to 15% of patients experience chronic cluster headache. Extended cluster headache periods dramatically hinders individuals with increased health care expenses. The initiating pathways for the cluster periods and individual attacks are still unknown. There is no doubt that treatment options are limited, and no disease-specific preventive medication exists.
JAMA neurology. 2018 Jul 9.
24min read
Key Take-Away:
The study results confirm that tocilizumab (TCZ) mono or combined therapy found to be safer and exhibited remarkable cardiovascular safety. A significant reduction of chemerin and increase of adiponectin in serum was observed in the patients subjected to the analysis.
Introduction:
Adipokines play an essential part in the pathophysiology of rheumatoid arthritis (RA), provide a link between the disease and overweight, explaining the enhanced cardiovascular (CV) risk. It also influences the response to disease-modifying antirheumatic drugs (DMARDs). This study aimed to determine the possible effects of intravenous (IV) tocilizumab (TCZ), an interleukin-6 receptor antagonist, on the serum levels of leptin, adiponectin, resistin, visfatin, and chemerin.
8min read
Key Take-Away:
The study affirms that the hybrid technique of fixation with osteochondral autograft transfer exhibited positive short-term outcomes and a low complication rate in patients with partially salvageable Osteochondritis Dissecans (OCD) lesions of the knee.
Introduction:
This retrospective case series explains a hybrid fixation method and determined the knee function, clinical outcomes, and activity level of patients when followed for short-term.
8min read
Education
Smart Guidelines
Pain is the leading cause of suffering, disability and medical care worldwide.
10 min read
Education
Presentations
Arthritis encompasses more than 100 different arthritic conditions which are a chronic, painful, and debilitating group of diseases.
15 min read
Education
Presentations
Rheumatoid arthritis (RA) is a chronic inflammatory disorder with an estimated prevalence of 0.5-1% of the population worldwide; it is also reported that women are more affected than men are. [1].
15 min read
Education
Presentations
Vitamins are organic compounds essential for normal physiological functions.
15 min read
Education
Presentations
The World Health Organization (WHO) describes the rational use of medicines as, “patients receive medications appropriate to their clinical needs, in doses that meet their own individual requiremen
5 min read
March 25, 2019
High-intensity laser therapy (HILT) along with exercise programs emerges as a beneficial therapeutic strategy for knee osteoarthritis (KOA) management, an analysis by the Department of Sports Medicine, School of Medicine, Iran University of Medical Sciences. KOA is considered as a prevalent joint disorder that leads to severe pain and functional disability.
Key Take-Away:
The results of the study conclude that both LMA and LTS-D are suitable and useful for airway treatment in patients breathing spontaneously during general anaesthesia for minor surgery of short duration.
The laryngeal mask airway LMA and laryngealube suction-disposable (LTS-D) is the second generation single-use supraglottic airway devices (SADs) with gastric access that are used for management of airway during general anaesthesia in spontaneously and mechanically ventilated patients.
Somri M et al. J Anaesthesiol Clin Pharmacol 2018;34:182-7
12min read
Education
Smart Guidelines
Pain is the leading cause of suffering, disability and medical care worldwide. Pain associated with chronic diseases are not life-threatening, but people continue to live with this pain in developed and developing countries affecting their overall quality of life.
10 min read