Pregabalin significantly improved pain and sleep quality, without clinically meaningful differences between diabetes types, reported by a recent study published in Current Medical Research and Opinion. B Parsons et al. conducted a study to differentiate between the efficacy and safety of pregabalin for painful diabetic peripheral neuropathy (pDPN) in patients with type 1 (T1DM) or 2 diabetes mellitus (T2DM).
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A study published in the journal- International Orthopaedics by Dikmen G et al. reported that a dual offset tapered stem attained excellent survivorship and stability, as well as good clinical outcome scores with minimum thigh pain and stress shielding in patients having arthritis and developmental dysplasia of the hip. Hence, a dual offset tapered stem may be an acceptable option for primary total hip arthroplasty in this group.
7min read
According to a recent analysis published in the journal Arthritis Care & Research, out of various knee bending forms among the individuals with knee osteoarthritis (OA), only prolonged kneeling showed a correlation with Hoffa‐synovitis prevalence on non‐contrast magnetic resonance imaging MRI.
6min read
These days nanotechnology‐based medicines, the nanomedicines (NMs) have gained attention as an effective treatment strategy to counter health issues like arthritis. Pre‐clinical research scientists, as well as physicians from all over the globe, support this approach.
6min read
A study published in the journal- Arthritis Research & Therapy used for the first time ever to assess the extent of monosodium urate (MSU) burden measured by dual-energy computed tomography (DECT) as a predictor of the risk of flares. Speculating the risk of flares in gout patients is a challenge. Also, the link between urate burden and the risk of gout flare has not been established clearly.
7min read
Key Take-Away:
Friedman BW et al. elucidated that Greater Occipital Nerve Blocks (GONB) might be an effective treatment for ED patients with an acute migraine, suffering from a moderate or a severe headache after the application of intravenous metoclopramide. But, this investigation was discontinued before achieving a priori sample size due to the slow enrollment.
Introduction:
It is believed that Greater occipital nerve block (GONB) is an effective treatment for acute migraine, but there has been no randomized efficacy data published for the same. It was hypothesized that bilateral GONB with bupivacaine may lead to greater rates of headache freedom than a sham injection among emergency department (ED) patients who described the persistence of a moderate or severe headache despite standard treatment with i.v. Metoclopramide.
9min read
Key Take-Away:
Abatacept is costimulation modulator used for the management of RA. In this study, the MRI of bilateral hands affirmed that Abatacept reduced synovitis and osteitis scores among RA patients and did not worsen erosion and JSN scores, but erosion started to repair in 10% of patients.
Introduction:
To investigate the efficacy of Abatacept among patients with rheumatoid arthritis (RA) applying magnetic resonance imaging (MRI) of bilateral hands.
7min read
Key Take-Away:
Osteoporosis can either cause thoracolumbar fractures (nontraumatic fracture) or may function as a contributing factor in cases of traumatic fractures. This study confirms that the application of polymethyl methacrylate augmented Cement-Injectable Cannulated Pedicle Screw (CICPS) as an effective and safe surgical method for the management of osteoporosis-related vertebral fractures with good clinical outcomes and low complications rates.
Introduction:
Assessment of the safety and efficacy of novel polymethyl methacrylate-augmented bone cement-injectable cannulated pedicle screw (CICPS) in patients with AO type A-thoracolumbar vertebral compression fractures associated with osteoporosis.
7min read
Key Take-Away:
Metabolic syndrome (MetS) has been shown to induce oxidative stress (OxS). This study clarifies the association of MetS with osteoarthritis and found a shift in the serum of OA patients, as indicator of of high-grade OxS and dysglycemia and the OA severity and MetS were independently associated with oxLDL.
Introduction:
Earlier investigations propose that metabolic disturbances might be correlated with the osteoarthritis (OA) development. Relationships have been observed among OA and the individual components of metabolic syndrome (MetS). MetS have been linked with enhanced oxidative stress (OxS). This study clarifies the MetS components role in OA and to assess the levels of OxS in OA subjects and in age-matched controls.
6min read
Key Take-Away:
A 59-year-old man and 62-year-old woman were presented with degenerative gonarthritis. They had no issues of breathing, pulse and blood pressure. They also had no consciousness or sensory disorders.
Which of the following methods could be the suitable management option for this case?
- NSAIDs
-
Knee Joint
-
Traction
-
Lateral knee injections
13min read
Education
Smart Guidelines
Pain is the leading cause of suffering, disability and medical care worldwide.
10 min read
Education
Presentations
Arthritis encompasses more than 100 different arthritic conditions which are a chronic, painful, and debilitating group of diseases.
15 min read
Education
Presentations
Rheumatoid arthritis (RA) is a chronic inflammatory disorder with an estimated prevalence of 0.5-1% of the population worldwide; it is also reported that women are more affected than men are. [1].
15 min read
Education
Presentations
Vitamins are organic compounds essential for normal physiological functions.
15 min read
Education
Presentations
The World Health Organization (WHO) describes the rational use of medicines as, “patients receive medications appropriate to their clinical needs, in doses that meet their own individual requiremen
5 min read
April 20, 2019
Pregabalin significantly improved pain and sleep quality, without clinically meaningful differences between diabetes types, reported by a recent study published in Current Medical Research and Opinion. B Parsons et al. conducted a study to differentiate between the efficacy and safety of pregabalin for painful diabetic peripheral neuropathy (pDPN) in patients with type 1 (T1DM) or 2 diabetes mellitus (T2DM).
Key Take-Away:
Friedman BW et al. elucidated that Greater Occipital Nerve Blocks (GONB) might be an effective treatment for ED patients with an acute migraine, suffering from a moderate or a severe headache after the application of intravenous metoclopramide. But, this investigation was discontinued before achieving a priori sample size due to the slow enrollment.
Introduction:
It is believed that Greater occipital nerve block (GONB) is an effective treatment for acute migraine, but there has been no randomized efficacy data published for the same. It was hypothesized that bilateral GONB with bupivacaine may lead to greater rates of headache freedom than a sham injection among emergency department (ED) patients who described the persistence of a moderate or severe headache despite standard treatment with i.v. Metoclopramide.
9min read
Education
Smart Guidelines
Pain is the leading cause of suffering, disability and medical care worldwide. Pain associated with chronic diseases are not life-threatening, but people continue to live with this pain in developed and developing countries affecting their overall quality of life.
10 min read