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On the basis of recent research published in the journal, Clinical Neurology and Neurosurgery, Tinnitus an objective or subjective sound listened inside the ear or brain presents as an audiology symptom by some of the migraineurs. As compared to the previous theory, tinnitus is restricted as an otologic ailment; current evidence supports it as a phantom sensory event of vestibulocochlear injury with the cortical reconstitution.

7min read    

The 14-strain probiotic mixture emerges as an efficient and useful supplement to alleviate migraine headaches within episodic and chronic migraineurs, as per a recently conducted trial by the faculties of Tehran University of Medical Sciences and Shahid Beheshti University of Medical Sciences. The thought behind the analysis is the association between migraine and GI disorders and the probiotics by suppressing various pathways could help to control the migraine.

8min read    

The Sacro-iliac joint (SIJ) is a diarthrodial joint located at the transition between the spine and lower limbs which is subjected to major shear forces. SIJ mobility is minimal but escalated during pregnancy and the post-partum period. Knowledge about the anatomy and physiology of the SIJ is crucial.

The SIJ connects two variably undulating cartilage surfaces, contains synovial fluid. It is enclosed within a capsule strengthened by several ligaments.

7min read    

Anakinra, a recombinant IL-1β receptor antagonist, was proved to be an effective treatment alternative for the acute gout flares as explained in the results of a randomized, double-blind, placebo-controlled, active comparator, non-inferiority (NI) trial study published in 'Rheumatology'.  Carly A Janssen et al. examined the efficacy and safety of anakinra in treating acute gout flares. 

8min read    

According to recent prospective randomized study results issued in the January edition of 'Journal of Anesthesia', sore throat is less common in Sevoflurane treated patients undergoing orthopaedic lower extremity surgery as compared to Desflurane. The tracheal intubation for general anaesthesia leads to a postoperative sore throat.

6min read    
Key Take-Away:

Endoscopic sinus surgery (ESS) is helpful for the treatment of chronic rhinosinusitis refractory to the conservative measures. In this trial, used as an adjunct to standard perioperative methods to reduce blood loss, the total intravenous anesthesia (TIVA) in comparison with volatile anesthetic improves intraoperative visualization during ESS.

Introduction:

Bleeding during endoscopic sinus surgery (ESS) can impede visualization and delay the surgical progress. The role that the anesthetic technique may have on the quality of the surgical field during ESS has been previously studied. But, the meta-analyses have considered the current literature inconclusive and lacking methodological consistency. This study was devised keeping these critiques in mind to assess the effect of TIVA versus inhaled anesthetic on the quality of surgical field during ESS.

8min read    
Key Take-Away:

This study reported that tofacitinib 10mg + MTX and baricitinib 4mg + MTX were the most efficacious interventions for rheumatoid arthritis patients with inappropriate response to disease-modifying anti-rheumatic drugs (DMARDs) or biologics therapy. Also, they were not associated with a significant risk of SAEs. But, long-term studies are awaited in a large number of patients with active RA that is inadequately responsive to MTX or biologics to determine the relative efficacy and safety of tofacitinib and baricitinib.

Introduction:

The relative efficacy and safety of tofacitinib and baricitinib were investigated in RA patients with an inadequate response to DMARDs or biologics.

8min read    
Key Take-Away:

This study, based on an international survey emphasis on the difficulty in establishing an unambiguous concept of difficult-to-treat rheumatoid arthritis (RA), which is seen as a heterogeneous condition and not fully covered by current EULAR recommendations. A more detailed survey is still needed to study the management of difficult-to-treat RA further and the recently established EULAR Task Force will explore the management of difficult-to-treat RA.

Introduction:

Patients with difficult-to-treat RA remain symptomatic despite treatment as per the current European League Against Rheumatism (EULAR) management recommendations. These aim at early phases of the disease and pharmacological management. The researchers tried to identify the characteristics of difficult-to-treat RA and issues in its management that are not covered by the current management recommendations.

7min read    
Key Take-Away:

Pregnancy modifies the immune state, most likely causing a change in the course of rheumatoid arthritis (RA). Hissay Aljary et al. evaluated in their cohort study that pregnant women are at a greater plausibility of adverse maternal and neonatal outcomes and they should also be made well-informed of these risks.
 

Introduction:

To investigate whether pregnancies in women with rheumatoid arthritis (RA) are at a higher risk of adverse maternal and neonatal outcomes.

7min read    
Key Take-Away:

This retrospective case series by Guo C et al. reported that supramalleolar osteotomy with intra-articular osteotomy had relatively good clinical results in the treatment of malunited medial impacted ankle fractures for maintaining ankle function. This is the right choice for the treatment of malunited medial impacted ankle fractures related to varus deformity. But, the surgeons should be aware of the loss of ankle motion post-operatively in most patients.

Introduction:

Malunion of a medial impacted ankle fracture may lead to varus ankle deformity. The use of supramalleolar osteotomy plus intra-articular osteotomy in patients with malunited medial impacted ankle fractures was explored in this study.

7min read    
Education
Smart Guidelines

Hand osteoarthritis (OA) is a common musculoskeletal disease, associated with hand pain, stiffness, functional limitation, decreased grip strength and reduced quality of life.

2min read    
Education
Smart Guidelines

Pain is the leading cause of suffering, disability and medical care worldwide.

10 min read    
Education
Presentations

Arthritis encompasses more than 100 different arthritic conditions which are a chronic, painful, and debilitating group of diseases.

15 min read    
Education
Presentations

Rheumatoid arthritis (RA) is a chronic inflammatory disorder with an estimated prevalence of 0.5-1% of the population worldwide; it is also reported that women are more affected than men are. [1].

15 min read    
Education
Presentations

Vitamins are organic compounds essential for normal physiological functions.

15 min read    
July 15, 2019

On the basis of recent research published in the journal, Clinical Neurology and Neurosurgery, Tinnitus an objective or subjective sound listened inside the ear or brain presents as an audiology symptom by some of the migraineurs. As compared to the previous theory, tinnitus is restricted as an otologic ailment; current evidence supports it as a phantom sensory event of vestibulocochlear injury with the cortical reconstitution.

Key Take-Away:

Endoscopic sinus surgery (ESS) is helpful for the treatment of chronic rhinosinusitis refractory to the conservative measures. In this trial, used as an adjunct to standard perioperative methods to reduce blood loss, the total intravenous anesthesia (TIVA) in comparison with volatile anesthetic improves intraoperative visualization during ESS.

Introduction:

Bleeding during endoscopic sinus surgery (ESS) can impede visualization and delay the surgical progress. The role that the anesthetic technique may have on the quality of the surgical field during ESS has been previously studied. But, the meta-analyses have considered the current literature inconclusive and lacking methodological consistency. This study was devised keeping these critiques in mind to assess the effect of TIVA versus inhaled anesthetic on the quality of surgical field during ESS.

8min read    
Education
Smart Guidelines

Hand osteoarthritis (OA) is a common musculoskeletal disease, associated with hand pain, stiffness, functional limitation, decreased grip strength and reduced quality of life. Its incidence increases with increasing age.

2min read