MSA and transoral incisionless fundoplication (TIF) were found to have a similar improvement in GERD-Health Related Quality of Life (GERD-HRQL) score, but MSA had better outcomes as compared to TIF2 in terms of patient satisfaction, after procedure regurgitation and the number of patients who stopped using PPI, concluded a study in Endoscopy international open. 

Saurabh Chandan et al. compared the efficacy of both procedures- MSA and TIF2 as evaluated via GERD-HRQL) score, patient satisfaction, improved after procedure regurgitation, and the number of patients who stopped using PPI therapy at follow-up.

After a widespread database search to recognize suitable studies, 24 studies with 1942 patients were included. Of particular interest, a significantly greater number of patients with MSA (91.1 %) described recovery in regurgitation compared to patients who opted for the TIF2 procedure (73.1 %). Furthermore, 91.3 % of patients with MSA were able to completely discontinue PPI therapy than only 63.8 % in TIF2. The body mass index and occurrence of a hiatal hernia in patients did not affect the procedural outcomes.