A recent meta-analysis depicted that for the management of nausea and vomiting during pregnancy, acupressure is beneficial. Nausea and vomiting during early pregnancy, commonly referred to as morning sickness, pose a significant challenge for pregnant women, impacting their daily lives and work routines. The use of medication to alleviate these symptoms can raise concerns about potential risks to the fetus. In light of this, researchers embarked on a mission to assess the effectiveness of acupressure, a non-pharmaceutical approach, in managing morning sickness.

Researchers conducted an extensive search across multiple databases, including Wanfang, VIP, CBM, CNKI, Web of Science, Cochrane, EMBASE, and PubMed using keywords such as 'pregnancy,' 'nausea,' 'vomiting,' and 'acupressure.' Two independent researchers meticulously screened articles, extracted data, and employed RevMan 5.4 software for rigorous statistical analysis. A comprehensive meta-analysis encompassing 33 trials and involving 3,390 patients unveiled promising results.

Acupressure emerged as an effective intervention for women experiencing nausea and vomiting during pregnancy, as indicated by the following outcomes:

• Acupressure remarkably improved nausea symptoms (odds ratio [OR] 4.81, 95% confidence interval (CI) [3.47, 6.68])
• The Rhodes index for nausea score exhibited a substantial reduction (mean square deviation [MD]: -3.21, 95% CI [-4.85, -1.57], Z = 3.83)
• The modified Pregnancy Unique Quantification of Emesis and Nausea score also showed marked improvement (MD: -2.18, 95% CI [-3.21, -1.15], Z = 4.15).
• Hospital stays were notably reduced (OR=-3.27, 95% CI [-6.18, -0.36]), contributing to a more comfortable pregnancy experience.
• Acupressure positively impacted the quality of life, with a vital reduction in scores (MD: -14.06, 95% CI [- 17.31, -10.18], Z = 8.48).

But, it's important to note that acupressure did not yield significant changes in nursing satisfaction and anxiety scores (OR=4.13, 95% CI [0.89, 19.15]) (MD: -13.26, 95% CI [-32.04, 5.53], Z = 1.38).

This meta-analysis offers compelling evidence supporting the use of acupressure as a non-pharmaceutical intervention for pregnant women experiencing nausea and vomiting. Acupressure effectively alleviates these distressing symptoms, potentially offering a safer and more comfortable option for expectant mothers.