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In older adults, vitamin K2 can help to decrease the occurrence, intensity, and duration of nighttime leg cramps without any safety concerns.
A randomized clinical trial depicted that vitamin K2 (menaquinone 7, 180 μg) supplementation dramatically lessens the frequency, severity, and persistence of nocturnal leg cramps (NLCs) in older individuals. With the goal to investigate vitamin K2 utility for tackling NLCs, this study involved community-dwelling adults (aged 65 years and older) if they experienced at least two NLC episodes within a two-week screening period.
Out of the 310 participants, 111 individuals were excluded from the study. A total of 199 eligible subjects (mean age 72.3 years) were randomly assigned to get either vitamin K2 (n=103) or a placebo (n=96) for 8 weeks.
Key findings:
Thus, vitamin K2 may serve as an effective and safe intervention for NLCs, a common yet often debilitating condition in older adults.
JAMA Internal Medicine
Vitamin K2 in Managing Nocturnal Leg Cramps: A Randomized Clinical Trial
Jing Tan et al.
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