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Atopic dermatitis affects nearly one in six Ethiopian children, with strong family history and fewer siblings emerging as key predictors.
A cross-sectional study published in "Scientific Reports" investigated atopic dermatitis (AD), a common chronic inflammatory skin disorder that often begins in infancy, within Ethiopia, where existing evidence was largely confined to single-facility studies. Investigators conducted this study among 420 kids seeking care at government-run dermatology clinics. To ascertain representativeness, study volunteers were chosen via a systematic random sampling technique.
Data were collected through an interview-administered questionnaire, and analysis was carried out utilizing the statistical package for the social sciences version 27.0.1. Descriptive statistics were applied for characterizing the population, while binary and multivariable logistic regressions were employed to explore factors linked with AD. The strength of associations was demonstrated using odds ratios with 95% confidence intervals (CI), and statistical significance was determined at a cut-off p-value of 0.05. The results demonstrated that among the 420 respondents, 225 (53.5%) were female, and the majority, 322 (76.6%), resided in urban areas.
The prevalence of AD was identified as 17.1% (95% CI: 13.7–21.1). Multivariate logistic regression analysis demonstrated vital predictors of AD. These included family history of atopic disease (adjusted odds ratio [AOR] 10.879), maternal asthma (AOR 9.908), paternal asthma (AOR 10.561), maternal allergic rhinitis (AOR 4.825), paternal allergic rhinitis (AOR 7.014), maternal AD (AOR 9.055), paternal AD (AOR 9.313), sibling history of atopic disease (AOR 11.750), and having fewer siblings (AOR 2.250).
This study identifies a higher prevalence of AD than earlier national reports, with strong links to family history and fewer siblings. The findings call for strengthened prevention strategies and targeted pediatric skin care interventions.
Scientific Reports
Magnitude of atopic dermatitis and associated factors among children in northwest Ethiopia
Alemu Bezabih Tegegnie et al.
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