This pilot study examined the impact of locally administered Betamethasone injections into the pterygomandibular space on postoperative neurosensory disturbance in individuals (ten females; six males; mean age: 24.95 ± 9.22 years) undergoing mandibular orthognathic surgical procedures.

In this prospective controlled clinical trial, abnormal light touch sensation was noted in 75% of the control group when compared to 31% in the experimental group, demonstrating significance (p = 0.03). However, by 6 months, all experimental cases regained touch sensation, contrasting with 69% in the control group. Although no noticeable disparity in direction movement discrimination was observed, the experimental side displayed remarkably fewer direction sensations (19%) as opposed to the control side (56%) at 3 months (p = 0.02).

Likewise, no pivotal difference was detected in two-point discrimination; nevertheless, at three months, the experimental side exhibited considerably fewer abnormal two-point sensations (13%) as opposed to the control side (56%) (p = 0.02). Thermal sensitivity and pin-prick sensation did not exhibit vital differences.

Betamethasone injection into the pterygomandibular space diminished neurosensory impairments following jaw surgery, aiding in faster sensory recovery.

The study involved 16 participants undergoing bilateral sagittal ramus osteotomy for mandibular discrepancies. Randomly, one side of each subject's mandible served as the control, while the opposite side was designated as the experimental group. Following wound closure, the experimental side received Betamethasone solution injections (6 mg/1 ml) into the pterygomandibular space.

Neurosensory assessments encompassing light touch, two-point discrimination, pin-prick discrimination, direction of movement, and thermal sensitivity were conducted. Follow-up duration ranged from six to twelve months, depending on the specific sensory test. For data evaluation, the Fisher exact test was utilized.