Dental biofilm–induced gingivitis (DB-GI) is a common inflammatory ailment of the gums in children and adolescents younger than 18 years.
Dental biofilm–induced gingivitis impacts nearly 52% of children and adolescents and requires effective plaque control, supervised toothbrushing, and targeted oral health education.
Dental biofilm–induced gingivitis (DB-GI) is a common inflammatory ailment of the gums in children and adolescents younger than 18 years. Its occurrence is influenced by multiple factors, including socioeconomic circumstances, oral hygiene practices, pubertal changes and malocclusion. Beyond gingival inflammation, the condition is linked with poorer oral health–related quality of life (OHRQoL), reinforcing the importance of early prevention and effective plaque control. However, variations in diagnostic criteria and the quality of available research complicate comparisons across studies. Hence, this systematic review sought to fill this gap.
Researchers explored PubMed Central, Scopus, Excerpta Medica Database (EMBASE) and Latin American and Caribbean Health Sciences Literature (LILACS) for relevant studies issued up to January 2025. Clinical trials and observational studies investigating gingival diseases or conditions in otherwise healthy individuals younger than 18 years were eligible for inclusion. Of the 33,180 studies identified, 2,264 remained after title and abstract screening, and 433 underwent full-text assessment. Ultimately, 269 studies were included.
All 269 included studies focused exclusively on DB-GI, though significant heterogeneity was identified across diagnostic criteria and study quality.
DB-GI affects 52% of children and adolescents without systemic conditions and negatively impacts OHRQoL. Successful management requires accessible, education-focused, and behavior-oriented biofilm control strategies, centered around supervised fluoridated toothbrushing and reinforced by caregiver and educational institutional support.
The Journal of Clinical Periodontology
Dental Biofilm–Induced Gingivitis in Children and Adolescents Without Known Systemic Involvement: A Systematic Review
Georgios Tsilingaridis et al.
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