The long-term use of calcium, vitamins D3 and B6 food supplements could be recommended to the osteoporosis patients undergoing medical rehabilitation. In combination with antiresorptive therapy, these supplements can also be beneficial in patients at a high risk of fractures. 

This study was based in Russia and included 119 osteoporosis patients (men and women both) those were at a high risk of fractures. The study population was divided into 3 groups as SG1, SG2 and SG3. The SG1 patients (n=41) received antiresorptive therapy, SG2 and SG3 group patients were those who have not received pathogenetic therapy for osteoporosis, were randomized as 39 in each group. 

The patients of SG1 and SG2 groups were prescribed a food supplement containing calcium salt and vitamin D3 and B6 to use within 12 months. Various parameters of rehabilitation in 20 days, 6 and 12 months from the start of the study were measured by Tensodynamometry, stabilometry and evaluation of functional tests of patients. All the parameters like muscle strength in extensor and flexor of the back among SG1 and SG2 group patients as compared to the initial level was maintained for 12 months. But in SG3 group, the effect of medical rehabilitation completely regressed after 6 months. Also, the 'stand on one leg' test results were found to be better in SG1 patients as compared to SG3 patients. It was found that without supplementation the medical rehabilitation deteriorated in SG3 patients.