In a research by Chrysoula Giourga et al., it was observed that low maternal Vitamin D levels are linked to the development of preeclampsia. Besides the immediate health risks for the mother during or after childbirth, such as the risk of mortality, deficient Vitamin D levels may also affect newborns and children. The aim of the study was to summarize and analyze the potential correlation between Vitamin D concentration in the serum of pregnant women and the risk of preeclampsia during pregnancy.

It also delved into whether levels of Vitamin D can serve as a protective factor, a risk factor, or even a prognostic indicator for the ailment. For conducting the literature review, searches were conducted on Scopus and PubMed utilizing the terms "Vitamin D" and "preeclampsia" to gather articles related to Vitamin D supplementation or serum levels in women with preeclampsia. The review included studies of all types, without language restrictions, except for animal studies.

Employing two distinct search strategies, a total of 261 and 36 studies were identified in Scopus and PubMed, respectively. Excluded from this review were duplicates and articles that lacked either full text or relevance. A total of  31 studies fulfilling the inclusion criteria were included into this review. As the dosage of Vitamin D elevated, the risk of preeclampsia dropped. Among the 31 articles, only 7 did not reveal a significant difference in Vitamin D levels in relation to preeclampsia, regardless of comorbidity. Hence, a connection exists between the levels of Vitamin D during pregnancy and the susceptibility to preeclampsia.