Trichoscopy and JAK inhibitors feature in new AA guidelines :- Medznat
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New APAC guidance advances alopecia areata management

Alopecia areata Alopecia areata
Alopecia areata Alopecia areata

What's new?

Asia-Pacific experts introduce updated alopecia areata guidelines emphasizing trichoscopy and targeted therapies.

Alopecia areata (AA) is an immune-mediated hair loss disorder that affects individuals across all age groups, genders, and ethnic populations while substantially impairing emotional well-being and quality of life (QoL). An expert panel aimed to establish practical, region-focused recommendations for the diagnosis, severity assessment, and treatment of AA across diverse healthcare settings in the Asia-Pacific (APAC) region.

Eighteen dermatology experts representing Australia, China, India, Korea, Malaysia, Singapore, Taiwan, and Thailand participated in a modified Delphi consensus process conducted over three rounds. The process included :

  • Structured surveys
  • Expert discussions
  • Statement-based voting

These were used to evaluate key aspects of AA management. Consensus for Likert-scale and multiple-choice statements was defined as at least 70% agreement or disagreement among panel members. The panel achieved consensus on 140 clinical statements addressing epidemiology, diagnosis, severity classification, and treatment strategies for AA.

  • Experts recognized the disease as clinically diverse and associated with a significant psychosocial burden for both patients and families.
  • Trichoscopy was identified as an essential tool for diagnosis and disease monitoring, whereas skin biopsy was recommended only when the cause of hair loss remained uncertain.
  • Moderate disease was classified as 21%–49% scalp hair loss, while severe AA was defined as hair loss affecting at least 50% of the scalp.
  • Topical corticosteroids were recommended for children younger than 12 years, while topical and intralesional corticosteroids were considered appropriate for mild-to-moderate disease in older patients.
  • Janus kinase (JAK) inhibitors and systemic corticosteroids were recognized as important therapeutic options for moderate-to-severe cases, with minoxidil suggested as an adjunct treatment in chronic disease.

The expert-driven consensus established a structured and clinically relevant framework for the diagnosis and management of AA within the APAC region. The recommendations strengthened the role of standardized assessment tools and evidence-based therapeutic strategies while addressing regional variations in healthcare practice. The guidance also underscored the growing importance of targeted therapies and early disease evaluation in improving long-term patient outcomes and QoL.

Source:

International Journal of Dermatology

Article:

Epidemiology, Diagnosis and Management of Alopecia Areata: An Asia-Pacific Modified Delphi Expert Panel Recommendations

Authors:

Rodney Sinclair et al.

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