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New Italian guidelines redefine functional dyspepsia care with streamlined diagnostic criteria, routine H. pylori testing, and tailored therapeutic recommendations.
Functional dyspepsia (FD) remains a frequently encountered yet often inconsistently managed gastrointestinal disorder, creating uncertainty in both diagnosis and therapeutic decision-making. To improve clinical practice and patient outcomes, a multidisciplinary Italian expert panel developed standardized, evidence-driven guidelines for the diagnosis and management of FD.
Experts representing five major Italian scientific societies in gastroenterology, endoscopy, neurogastroenterology, and general medicine conducted a structured Delphi consensus process. The initiative incorporated a comprehensive review of the available scientific literature and evaluated 24 key clinical statements related to the diagnosis and treatment of FD. Each recommendation received an evidence-based grade via the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) framework. An 80% agreement rate among the panelists served as the criterion for consensus.
The consensus panel formulated an extensive approach to FD diagnosis and management, offering key guidance for clinical practice.
Overall, the recommendations outlined a structured, evidence-based approach that prioritizes targeted investigations, H. pylori eradication, and symptom-directed treatment strategies for FD-affected patients. The consensus marked an important step towards standardizing FD care, translating current evidence into practical recommendations that can support more accurate diagnoses, rational treatment decisions, and improved patient outcomes across clinical settings.
Digestive and Liver Disease
Italian guidelines for the diagnosis and treatment of functional dyspepsia - joint consensus from the Italian societies of gastroenterology and endoscopy (SIGE), Neurogastroenterology and motility (SINGEM), hospital gastroenterologists and endoscopists (AIGO), digestive endoscopy (SIED) and general medicine (SIMG)
Giovanni Sarnelli et al.
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