The oral route of drug administration is the most preferred route which offers many benefits such as accurate dosage, low cost therapy, good stability, self-medication etc.
Expert Drug Opinion
Non-steroidal anti-inflammatory drugs are the choice of treatment for various clinical disorders such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, gout, dysmenorrhea, dental pain and headache.
NSAIDs display anti-inflammatory, anaesthetic and antipyretic effects and indicated for the relief of acute and chronic pain in a wide variety of clinical disorders. They act via blockade of pro-inflammatory enzyme cyclooxygenase
NSAIDs are extensively used for the management of chronic painful conditions such as OA, RA and to alleviate pain and inflammation associated with other diseases.
Nimesulide is a non-acidic selective COX 2 inhibitor with anti-inflammatory, analgesic and antipyretic activities. Nimesulide has a faster onset of action, relatively low GI and nephrotoxicity and in patients who experience respiratory problems with other NSAIDs.
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