B vitamins helps maintain the body functions, including repair, development, and growth. In the peripheral nervous system, they promote the acceleration of nerve repair, both in enhancement of nerve regeneration and the recovery of nerve function.
Neuropathic pain is becoming a major concern worldwide; a significant section of world population is under the influence of this form of pain. The developed countries like Russia, Japan, China and US are highly impacted by neuropathic pain.
As per the Russian guidelines, NSAIDs are the most important and popular class of analgesics recommended for relieving moderate or severe pain. These drugs are effective and convenient to use, but the precautions are necessary to avoid serious complications of gastrointestinal tract, cardiovascular system, kidneys, etc.
Large chronic pain population studies are lacking, and those available often neglect psychosocial characteristics of chronic pain. Data gathered from a large population suffering from chronic pain referred to a multidisciplinary academic pain clinic in the Netherlands may provide insights for further research, therapy, and information about frequently overlooked aspects.
The factors that cause neck pain and increase or decrease the pain can vary widely, and the neck pain mechanism is not yet fully explained. So, when evaluating the patients with chronic neck pain (CNP), it should be evaluated not only for the individual's pain but also for the biopsychosocial model. It is known in recent years that; pathologies cause inadequacies, inadequacies cause functional limitations, and functional limitations cause disability. For this reason, besides the pain of the patients with CNP, it is important that they are evaluated in terms of their functional states. The level of disability generally increases in patients with CNP. In addition, CNP increases the tendency to depression and levels of kinesophobia of these patients. Factors such as depression and kinesiophobia can negatively affect the level of disability by reducing motivation of patients and participation in social life. There are many reasons that increase the level of disability in these patients. The aim of this study is to assess the relationship pain, depression and kinesophobia with level of disability in patients with CNP and to determine which parameter most important factor for disability.
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