Clinical Research

Key Take-Away:

The results of the study conclude that both LMA and LTS-D are suitable and useful for airway treatment in patients breathing spontaneously during general anaesthesia for minor surgery of short duration.

The laryngeal mask airway LMA and laryngealube suction-disposable (LTS-D) is the second generation single-use supraglottic airway devices (SADs) with gastric access that are used for management of airway during general anaesthesia in spontaneously and mechanically ventilated patients.

Somri M et al. J Anaesthesiol Clin Pharmacol 2018;34:182-7
12min read    
Key Take-Away:

The results of this study indicate the use of the unloading knee brace in combination with usual care as a safe and superior therapy in relieving global pain and improving motion as compared to routine care.

Knee osteoarthritis (OA) refers to a common disabling disorder that leads to considerable pain, immobility, functional impairment and reduced quality of life. It becomes prevalent as the age of the population increases.

Philippe Thoumie et al. Scientific Reports. (2018) 8:10519
15min read    
Key Take-Away:

The study concluded that the calcitonin gene-related peptide provoke cluster headache attacks in active-phase episodic cluster headache and chronic cluster headache but not in remission-phase episodic cluster headache. These results suggest anti-CGRP drugs may be useful in cluster headache management.

Cluster headache is a chronic headache disorder with a prevalence of 0.5 to 1.0 out of the population of 1000. Cluster headache attacks are characterised by prominent ipsilateral cephalic autonomic symptoms (CAS), such as tearing, conjunctival redness, rhinorrhea or nasal congestion, ptosis, as well as the sense of agitation or restlessness. Most of the patients experiencing episodic cluster headache with month-long attack periods separated by remission periods. The remaining 10% to 15% of patients experience chronic cluster headache. Extended cluster headache periods dramatically hinders individuals with increased health care expenses. The initiating pathways for the cluster periods and individual attacks are still unknown. There is no doubt that treatment options are limited, and no disease-specific preventive medication exists.

JAMA neurology. 2018 Jul 9.
24min read    
Key Take-Away:

Thiazide diuretic may decrease the risk of fracture, indicating the protective effect of this class in clinical practice.

Osteoporosis is a major chronic condition worldwide, and the major health issue in the USA especially in the aging population. About 300,000 people aged 65 and older are hospitalized each year due to hip fracture, a situation which often leads to decreased quality of life.

Osteoporosis Int. 2018 Mar 25
20min read    
Key Take-Away:

In middle-aged people with mild radiographic osteoarthritis (OA), structural features changes do occur  a little over a year, irrespective of weight patients loss status.

Osteoarthritis (OA) is a principal cause of disability and a more massive public health problem in the United States.

Osteoarthritis and Cartilage
20min read