Abstracts

Key Take-Away:

Chronic widespread pain (CWP) associated with fibromyalgia is a prevalent condition with a range of physical and psychological disabling symptoms. Previous studies predicted that various lipid mediators and cytokines could serve as markers of alterations in chronic pain. The present study revealed that circulating levels of N-acylethanolamines might be a better indicator of systemic inflammation in CWP than the investigated cytokines.

Chronic widespread pain conditions (CWP) such as the pain associated with fibromyalgia syndrome (FMS) are significant health problems with unclear aetiology. Although CWP and FMS can alter both central and peripheral pain mechanisms, there are no validated markers for such alterations.

Lipids Health Dis. 2017 Jun 12;16(1):112
6min read    
Key Take-Away:

In the management of women with knee OA strengthening of weak knee muscles, improving limited flexion ROM, pain management, weight loss, and improving anxiety should be considered as a priority, and performance-based and self-reported measures should be used together for a comprehensive evaluation of physical functioning.

Knee osteoarthritis (OA) is an important health problem with its high prevalence and association with pain and functional disability in physical tasks and activities, especially in women. 

Aging Clin Exp Res. 2017 Jun 12.
7min read    
Key Take-Away:

The effectiveness of controlled-release Pregabalin in post herpetic neuralgia has not been explored in the previous studies. The investigators of the present comparative analysis study were successful in assessing the efficacy and safety profile of controlled and immediate release formulation of pregabalin in nerve pain management.

To assess efficacy and safety of once-daily controlled-release (CR) formulation of pregabalin in patients with postherpetic neuralgia.

The Clinical Journal of Pain
5min read    
Key Take-Away:

Chronic musculoskeletal disorders are a prevalent and costly global health issue. A new form of exercise therapy focused on loading and resistance programmes that temporarily aggravate a patient's pain has been proposed. 

Chronic musculoskeletal disorders are a prevalent and costly global health issue. A new form of exercise therapy focused on loading and resistance programmes that temporarily aggravate a patient's pain has been proposed. 

British Journal of Sports Medicine
5min read    
Key Take-Away:

Psoriasis is the most persistent inflammatory skin disease that may lead to psoriatic arthritis. There is a great need to distinguish psoriatic arthritis from psoriasis without psoriatic arthritis. In this study, the potential of various serum biomarkers like CD5L, ITGΒ5, M2BP, MPO, MMP3, and CRP has been studied, and it has been deduced that the combination of serum biomarkers can be helpful in differentiating psoriatic arthritis from psoriasis without psoriatic arthritis.

There is a high prevalence of undiagnosed psoriatic arthritis (PsA) in psoriasis patients. Identifying soluble biomarkers for PsA will help in screening psoriasis patients for appropriate rheumatology referral.

Arthritis care res (Hoboken). 2017 jun 6
5min read