Frequency and features of the central poststroke pain

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Frequency and features of the central poststroke pain
Key Take-Away: 

Central poststroke pain is debilitating morbidity that affects the large ratio of patients with stroke. The following analysis demonstrated that younger patients with thalamic stroke should be carefully examined for the presence of neuropathic pain as it may influence the therapeutic strategy and quality of life of these patients.

Central poststroke pain (CPSP) is a condition which may exacerbate the recovery and diminish the quality of life. It is not well-known in clinical practice. This study aimed to recognise characteristics and the incidence of CPSP, as well as to make potential connections of CPSP with clinical and sociodemographic attributes of subjects with stroke.



A total of 602 patients with prior stroke were tested sequentially in two years. The Leeds Assessment of Neuropathic Symptoms and Signs - LANSS, Pain Detect Questionnaire - PD-Q, and Douleur neuropatathique en 4 questions were used to investigate the neuropathic pain.



A total of 12% of stroke patients showed CPSP, usually in the first several months following stroke. It exhibited a connection between the higher level of functional disability, younger age and cortical and thalamic localisation of stroke. The presence of allodynia and pricking hypoesthesia differentiated CPSP from the other types of pain.



Younger patients with thalamic/cortical stroke with the significant disability should be examined carefully for the neuropathic pain presence, since this may profoundly influence therapeutic approach and quality of life in such patients.


J Neurol Sci

Link to the source:

Original title of article:

Frequency and features of the central poststroke pain.


Zoran Vukojevic et al.

Exploratory, Poststroke pain, Brain, LANSS, PD-Q, DN4
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