Ziziphus jujuba syrup is effective and safe to treat pediatric functional constipation with better outcomes than polyethylene glycol.
In a randomized clinical trial led by Fatemeh Keihanian et al., Ziziphus jujuba syrup (ZS), a traditional herbal remedy, appeared to be a safe and effective intervention for functional constipation in children, potentially offering a promising alternative to polyethylene glycol (PEG). The study, conducted in Iran, involved 90 children aged 2–10 with diagnosed functional constipation. Volunteers were randomized to:
The enrolled children were monitored for 3 months. Follow-ups were carried out every 2 weeks during the first 30 days and monthly for the next 2 months. Liver and kidney function tests, along with blood sugar levels, were conducted at both the beginning and end of the trial.
Key results:
With no significant liver or kidney damage and notable improvements in symptoms, ZS shows promise as an effective, low-cost, and well-tolerated alternative for tackling pediatric functional constipation. However, additional research is warranted to determine its long-term safety.
Scientific Reports
Comparison of Ziziphus jujube Mill. Syrup versus polyethylene glycol in children with functional constipation: a randomized clinical trial
Fatemeh Keihanian et al.
Comments (0)