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Thyme honey mouthwash significantly relieves polypharmacy-induced xerostomia while improving patient-reported oral comfort.
A natural thyme honey oral rinse markedly increases salivary flow, reduces oral dryness, and improves quality of life in patients with polypharmacy-induced xerostomia, according to a randomized controlled clinical trial from Egypt.
Xerostomia, or chronic dry mouth, is increasingly common due to the rising prevalence of systemic diseases and long-term use of multiple medications. Reduced salivary secretion negatively impacts oral health, comfort, nutrition, and daily activities. With limited safe long-term treatment options available, interest has grown in natural salivary stimulants as alternative therapies.
Researchers conducted a randomized controlled clinical trial involving 64 adults experiencing xerostomia while taking two or more xerostomia-inducing drugs. Participants were randomly allocated to:
Both groups utilized their assigned rinse 3 times daily for 4 weeks. The investigators evaluated unstimulated salivary flow rate (USFR), subjective dryness score, clinical oral dryness score at baseline, 2 weeks, and 4 weeks. Additionally, the following were assessed at baseline and after 4 weeks: Salivary nitric oxide levels, and xerostomia-related quality of life scale (XeQoLS). After 4 weeks of treatment:
Hence, thyme honey mouth rinse is a valuable non-pharmacological and natural intervention for tackling xerostomia caused by polypharmacy. Its ability to enhance salivary secretion while improving patient-reported outcomes positions it as a promising adjunct in oral care.
Journal of Stomatology Oral and Maxillofacial Surgery
The efficacy of thyme honey mouth rinse on polypharmacy-induced xerostomia: A randomized controlled clinical trial with a biochemical assessment
Suzan S. Ibrahim et al.
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