Categories
Change Password!
Reset Password!
Patients with mild dementia experience improved cognition, decreased gut infection, and reduced BMI after black raspberry supplementation.
A new study has uncovered compelling evidence that black raspberries (BRBs) may offer a triple-action benefit for people with mild Alzheimer’s disease who are also overweight and infected with Helicobacter pylori (H. pylori). The study, focused on the gut-brain axis—a key communication network between the gut and brain—suggests that BRBs can remarkably enhance cognitive function, decrease harmful gut bacteria, and support healthy weight.
Researchers conducted a 10-week randomized clinical trial involving individuals with mild clinical dementia, H. pylori infection, and a body mass index (BMI) above normal. Participants were randomly assigned to get either 25 grams of freeze-dried BRB powder or a placebo, taken twice daily (morning and evening) over an 8-week intervention period, followed by a 2-week follow-up. Results showed that BRB supplementation led to significant improvements across all three primary measures compared to the placebo group:
Beyond these core outcomes, the BRB group also saw meaningful reductions in inflammatory markers, improvements in antioxidant balance, and increased levels of adiponectin, a hormone linked to metabolic health (p < 0.05). However, there were no vital differences in adenosine monophosphate-activated protein kinase (AMPK) and leptin levels between groups. Notably, BRBs also modulated the gut microbiome, increasing the abundance of beneficial bacteria—especially Akkermansia muciniphila, a species connected with improved metabolic and immune function.
These results support the growing theory that restoring gut health may directly benefit brain function in early Alzheimer’s disease. By simultaneously reducing H. pylori infection and body weight, BRBs appear to help rebalance the gut microbiome, potentially enhancing communication along the gut-brain axis.
npj Science of Food
Black raspberry supplementation on overweight and Helicobacter pylori infected mild dementia patients a pilot study
Yohanes Tandoro et al.
Comments (0)