Abstracts

Key Take-Away:

Oral Glucocorticoids are therapeutic agents that exhibit anti-inflammatory properties. As per these study results, there has been an association in Glucocorticoid use and osteonecrosis in a dose-related fashion in adults but not in children.

Introduction:

8min read    
Key Take-Away:

Previous studies presented limited evidence for the occurrence of mortality in patients with chronic widespread pain (CWP). This study results affirmed that individuals with CWP experience excess mortality. For which the adverse lifestyle factors may be a culprit. Thus for management of CWG lifestyle modifications could be adopted.

Introduction:

It is not clear whether individuals with widespread chronic pain (CWP) undergo premature mortality. This study investigated whether the correlation exists, also estimated its magnitude and discovered what factors interfere with the connection.

 

7min read    
Key Take-Away:

Impairment in motor control can occur in non-specific low back pain (NSCLBP). The study results suggested that there are differences in the lower thoracic region between spinal kinematics in NSCLBP subgroups and healthy participants. It was observed that during functional tasks the thoraco-lumbar spine exhibited a marked difference between FP and AEP, and FP and healthy groups.

Introduction:

A multidimensional classification strategy recommends that motor control impairment subgroups are present in non-specific chronic low back pain (NSCLBP). Variations in sitting lumbar posture have been recognised between healthy individuals and two such subgroups [active extension pattern (AEP) and flexion pattern (FP)]; although, the functional spinal movement had not been investigated. This study evaluated whether NSCLBP subgroups present regional spinal kinematic variations than healthy people during functional tasks.

7min read    
Key Take-Away:

The study results confirm that tocilizumab (TCZ) mono or combined therapy found to be safer and exhibited remarkable cardiovascular safety. A significant reduction of chemerin and increase of adiponectin in serum was observed in the patients subjected to the analysis.

Introduction:

Adipokines play an essential part in the pathophysiology of rheumatoid arthritis (RA), provide a link between the disease and overweight, explaining the enhanced cardiovascular (CV) risk. It also influences the response to disease-modifying antirheumatic drugs (DMARDs). This study aimed to determine the possible effects of intravenous (IV) tocilizumab (TCZ), an interleukin-6 receptor antagonist, on the serum levels of leptin, adiponectin, resistin, visfatin, and chemerin.

8min read    
Key Take-Away:

The study affirms that the hybrid technique of fixation with osteochondral autograft transfer exhibited positive short-term outcomes and a low complication rate in patients with partially salvageable Osteochondritis Dissecans (OCD) lesions of the knee.

Introduction:

This retrospective case series explains a hybrid fixation method and determined the knee function, clinical outcomes, and activity level of patients when followed for short-term.

8min read