Key Take-Away:

Friedman BW et al. elucidated that Greater Occipital Nerve Blocks (GONB) might be an effective treatment for ED patients with an acute migraine, suffering from a moderate or a severe headache after the application of intravenous metoclopramide. But, this investigation was discontinued before achieving a priori sample size due to the slow enrollment.

Introduction:

It is believed that Greater occipital nerve block (GONB) is an effective treatment for acute migraine, but there has been no randomized efficacy data published for the same. It was hypothesized that bilateral GONB with bupivacaine may lead to greater rates of headache freedom than a sham injection among emergency department (ED) patients who described the persistence of a moderate or severe headache despite standard treatment with i.v. Metoclopramide.

9min read    
Key Take-Away:

Abatacept is costimulation modulator used for the management of RA. In this study, the MRI of bilateral hands affirmed that Abatacept reduced synovitis and osteitis scores among RA patients and did not worsen erosion and JSN scores, but erosion started to repair in 10% of patients.

Introduction:

To investigate the efficacy of Abatacept among patients with rheumatoid arthritis (RA) applying magnetic resonance imaging (MRI) of bilateral hands.

7min read    
Key Take-Away:

Osteoporosis can either cause thoracolumbar fractures (nontraumatic fracture) or may function as a contributing factor in cases of traumatic fractures. This study confirms that the application of polymethyl methacrylate augmented Cement-Injectable Cannulated Pedicle Screw (CICPS) as an effective and safe surgical method for the management of osteoporosis-related vertebral fractures with good clinical outcomes and low complications rates.

Introduction:

Assessment of the safety and efficacy of novel polymethyl methacrylate-augmented bone cement-injectable cannulated pedicle screw (CICPS) in patients with AO type A-thoracolumbar vertebral compression fractures associated with osteoporosis.

7min read    
Key Take-Away:

Metabolic syndrome (MetS) has been shown to induce oxidative stress (OxS). This study clarifies the association of MetS with osteoarthritis and found a shift in the serum of OA patients, as indicator of of high-grade OxS and dysglycemia and the OA severity and MetS were independently associated with oxLDL.

Introduction:

Earlier investigations propose that metabolic disturbances might be correlated with the osteoarthritis (OA) development. Relationships have been observed among OA and the individual components of metabolic syndrome (MetS). MetS have been linked with enhanced oxidative stress (OxS). This study clarifies the MetS components role in OA and to assess the levels of OxS in OA subjects and in age-matched controls.

6min read    

A 59-year-old man and 62-year-old woman were presented with degenerative gonarthritis. They had no issues of breathing, pulse and blood pressure. They also had no consciousness or sensory disorders.

 

Which of the following methods could be the suitable management option for this case?

  • NSAIDs
  • Knee Joint

  • Traction

  • Lateral knee injections

13min read