The Tofacitinib, a JAK inhibitor presents the excellent potential for psoriasis and psoriatic arthritis treatment, as per recent research carried out by the scientists of Chapel Allerton Hospital and Bradford Teaching Hospitals. These are the immune-mediated health issues leading to significant functional disability and reduced quality of life. Further, due to clinical heterogeneity associated with these problems, the management becomes difficult.
As per a recently published systematic review and meta-analysis in the Journal, Rheumatology International, out of the five major classes of drugs; oral NSAIDs, topical NSAIDs, COX-2 inhibitors, opioids and acetaminophen; topical NSAIDs exhibited higher efficiency in the management of osteoarthritis-associated pain.
According to a current observational cohort study published in the Journal Headache, 3.16% of patients who underwent catheter‐based cerebral angiography were experiencing the episodes of a migraine headache. Cerebral angiography, an x-ray examination method is the most reliable mode to inspect the blood vessels of the brain by inserting a catheter through a small cut in the skin of leg or arm.
The diabetic peripheral neuropathy could be managed with non-pharmacological interventions like alpha-lipoic acid and spinal cord stimulation; said the scientists of Hopkin Hospital, Baltimore, USA.
Some diabetic neuropathy patients may not be adequately relieved with conventional therapies or may face adverse effects. Thus, the scientists focused on evaluating the efficacy and safety of some non-pharmacological treatments by conducting a systematic analytical review.
A detailed systematic review and meta-analysis discovered the remarkable results after spinal cord stimulation in attenuating specific chronic pain syndromes and helped patients on returning to work. Due to the considerable adverse effect of chronic pain on work-related outcomes, the efficiency of interventions to reduce the disease burden gets underscore.