News
April 24, 2019

The osteoarthritis-associated moderate to severe pain can be managed up to 24 weeks with the intra-articular 1.0 mg CNTX‐4975 (synthetic trans‐capsaicin), presents significant efficacy and safety of trans-capsaicin.

A total of 172 participants with stable knee osteoarthritis were selected and randomized to receive either of a placebo, CNTX‐4975 0.5 mg, or CNTX‐4975 1.0 mg. The efficacy of CNTX‐4975 was evaluated.

6min read    
News
April 24, 2019

Chronic migraine (CM) is a severe enervate disorder which affects about 2% of the general population. Only two approaches have displayed the efficacy in treating CM, one is OnabotulinumtoxinA, and the other is Topiramate. As compared to the conventional treatment, OnabotulinumtoxinA shows some difficulties with orally delivered preventatives for headache specialists not practised to injecting toxins.

9min read    
News
April 24, 2019

The migraineurs experienced significant relief in dry eye symptoms and photophobia with the administration of Botulinum toxin A, independent of baseline tear film volume, as per the findings of a retrospective analysis published in the British Journal of Opthalmology.

A total of 76 migraineurs from a Miami Veterans Affairs Medical Center Neurotoxin Clinic who obtained BoNT-A from 23 August 2017 to13 December 2017 were selected for the analysis.

7min read    
News
April 23, 2019

The International Headache Society Clinical Trials Standing Committee introduced the fourth edition of the Guidelines for controlled trials of drugs in migraine. First edition of these Guidelines was published in 1991, and the goal was to enhance the quality of controlled clinical trials via promoting the adoption of scientifically robust approaches in clinical research.

7min read    
News
April 23, 2019

Various study findings have shown that IV lidocaine could be the potential alternative to manage primary and secondary headache. Generally, IV lidocaine is widely used as a local anaesthetic in the emergency department (ED) setting as well as for perioperative pain management.

8min read