Various features and responses atypical odontalgia to drugs

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Various features and responses atypical odontalgia to drugs

Atypical odontalgia (AO)/ phantom tooth pain/ non-odontogenic tooth pain is a complex throbbing in the tooth without significant pathology. It is an ongoing pain which affects the teeth or tooth sockets following extraction in the absence of any visible cause on clinical or radiographic examination. The diagnosis and treatment of pain in the orofacial region is a difficult task as comprise of mixed tissues. The efficacy of antidepressants like amitriptyline differs as per the case and severity of AO.

Miho Takenoshita et al. Delineated three types of AO and discussed its heterogeneity and management. The first case considered was a 58-year-old woman who had hefty, splitting pain in maxillary front post-crown teeth (four), as if they were forced from the side. Her symptoms eased with amitriptyline 20mg. As for the second case, a 39-year-old woman had severe pain on the right side of maxillary and mandibular molar teeth, face, palate as well as throat. Her pain disrupted her daily functions. She had difficulty in her performing her daily chores. Her symptoms drastically improved with aripiprazole 3 mg. The third case was a 54-year-old woman who had a tingling sensation in the left mandibular second premolar and first molar. She had an uncomfortable feeling on her provisional prosthesis that made it intolerable to keep the caps on. Her symptoms improved with aripiprazole 2mg added to mirtazapine 30mg.

It was revealed that AO portrays many features and responses to drugs. This was regarded as a purely sensory as well as a considerably complex psychological problem, like rumination about the pain. A thorough examination of the contrast in pharmacotherapeutic responses might help to facilitate the treatment of AO.


BioPsychoSocial Medicine

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Original title of article:

Clinical features of atypical odontalgia; three cases and literature reviews


Miho Takenoshita et al.

Diagnostic, Amitriptyline, Pain, Atypical odontalgia, Tooth, Antidepressants, Efficacy
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