Therapeutic Exercise and Botulinum Toxin Type A or Hyaluronate Injection can Improve Knee Functioning

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Therapeutic Exercise and Botulinum Toxin Type A or Hyaluronate Injection can Improve Knee Functioning

In a recent study, the effect of therapeutic exercise was evaluated on knee function after injection of botulinum toxin type A, hyaluronate or saline.

Sixty participants with knee osteoarthritis were randomly divided into 3 groups: injection of saline (control) (group A), botulinum toxin type A (group B), or hyaluronate (group C). All the participants received therapeutic exercise. Western Ontario and McMaster Universities Osteoarthritis Index questionnaire score, visual analogue scale (VAS) pain scale, and Medical Outcomes Study 36-Item Health Survey were conducted at baseline, and at the end of the 4th and 8th weeks.
At the completion of the 4th and 8th weeks, the scores on the Western Ontario and McMaster Universities Osteoarthritis Index questionnaire and visual analogue scale were reported to be higher in the control group. There were significant differences in Mental Component Summary-36 and Physical Component Summary-36 scores between all the three groups with p < 0.05 at the completion of the 4th and 8th weeks, but not between groups A (control) and C (hyaluronate) at the end of the 4th week. Magnetic resonance imaging and X-ray images did not show any changes in images of the affected knees after the intervention.

Thes study concluded that therapeutic exercise with botulinum toxin type A or hyaluronate injection could reduce pain and improve knee functioning significantly. Moreover, botulinum toxin type A plus therapeutic exercise appeared to be more effective.

Source:                       

Department of Rehabilitation Medicine

Link to the source:

https://www.ncbi.nlm.nih.gov/pubmed/29664106

The original title of the article:

Effect of therapeutic exercise on knee osteoarthritis after intra-articular injection of botulinum toxin type A, hyaluronate or saline: A randomized controlled trial.

Authors

Bao; X. et al.

SearchTags: 
Therapeutic, Botulinum toxin, Osteoarthritis, Knee, Therapeutic exercise, , Visual analogue scale, Intra-articular.
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