A Study finds Strong Connection between Knee Load and Pain during Walking in Knee Osteoarthritis Patients

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A Study finds Strong Connection between Knee Load and Pain during Walking in Knee Osteoarthritis Patients

A recent case‐control study by Trevor B Birmingham et al. in 'Arthritis Care and Research' journal described that when between‐patient confounding is reduced, there is a strong association between medial knee load and increased knee pain during walking.

There is low evidence about the connection between knee loading and pain in knee osteoarthritis (OA) patients and of questionable significance, but may be confounded by many factors that vary between patients. This, within‐patient, between‐knees, case‐control study clarified about the connection between dynamic knee load and pain by minimizing confounding.

All in all, 265 patients with knees discordant for pain (530 knees) noted the pain in each knee before and after walking for 6 minutes. After that, they underwent three‐dimensional gait analysis.

Increased pain (odds ratio 2.43, 95% confidence interval 1.77 to 3.33; and 6.62, 3.46 to 12.7, respectively) was concerned with the peak knee adduction moment and knee adduction impulse (proxies for medial knee loading). This remained significant after controlling for radiographic disease severity. The quartiles were split into two, the knees in the highest loading quartile had 4.7 (2.3 to 9.5; peak adduction moment) and 9.0 (4.0 to 20.1; knee adduction impulse) times higher odds of encountering increased pain with walking as compared to knees in the lowest loading quartile.

Source

Arthritis Care and Research

Link to the source

https://onlinelibrary.wiley.com/doi/abs/10.1002/acr.23704

Original title of the article

Association Between Knee Load and Pain: Within‐Patient, Between‐Knees, Case‐Control Study in Patients with Knee Osteoarthritis

Authors

Trevor B Birmingham et al.

SearchTags: 
Exploratory, Osteoarthritis, Pain, Knee, Joints, Case‐Control Study, Gait analysis
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