Scientists Confirmed the Presence of Sarcopenia in a Significant Proportion of Rheumatoid Arthritis Patients

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Scientists Confirmed the Presence of Sarcopenia in a Significant Proportion of Rheumatoid Arthritis Patients

According to a recent study published in the Journal "Modern Rheumatology," Sarcopenia occurs in a significant portion of Rheumatoid arthritis (RA) patients. Also, the factors like age, longer disease duration, joint destruction, and malnutrition were found to be positively associated with sarcopenia while the negative association was observed with the use of bDMARDs.

Sarcopenia is an age-related condition marked by reduced muscle mass and strength. The loss of muscle strength leads to serious adverse health issues. This cross-section study aimed to evaluate the incidence rate of sarcopenia and related factors in RA patients.

A total of 388 consecutive females with RA were selected to analyze walking speed, muscle strength, and mass. Falls and bone fractures existed over the previous year were examined. Logistic regression analyses were utilized to estimate the correlation between sarcopenia and RA features, bone fractures and falls.

The incidence rate of sarcopenia was found to be 37.1%, out of which 49% exhibited low muscle mass. The RA patients with sarcopenia showed lower bone mineral density along with the higher rate of fractures and falls as compared to patients without sarcopenia. The independent factors related with sarcopenia were steinbrocker's stage, bDMARDs use, RA duration, age, and the high Mini-Nutritional Assessment-short form score. The overall results suggest the presence of sarcopenia and related complications: lower bone density with the higher risk of fractures in a significant proportion of RA patients.

Source

Modern Rheumatology

the source:

https://www.tandfonline.com/doi/abs/10.1080/14397595.2018.1510565

Original title of the article:

Prevalence and factors associated with sarcopenia in patients with rheumatoid arthritis

Authors:

Mie Torii et al.

SearchTags: 
Exploratory, Rheumatoid Arthritis, Joints, Cross-section Study
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