RAPID3 scores can indicate the functional ability of rheumatoid arthritis

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RAPID3 scores can indicate the functional ability of rheumatoid arthritis

As per this preliminary study, Routine Assessment of Patient Index Data 3 (RAPID3) scores were strongly correlated with measurements of the functional ability of the hand. RAPID3 is a patient-reported disease activity measure used to estimate physical function, pain and global health in patients with rheumatoid arthritis (RA) without formal joint counts.

Rheumatoid arthritis is often marked limited functions of the affected joint. Qorolli M, et al., examined the performance of RAPID3 scores with respect to hand function and to affirm previous findings that the RAPID3 score is a disease activity score (DAS) measure and is firmly correlated with the DAS28 score.

A total of 68 consecutive patients suffering from RA (85% female), aged 18–75 years, were considered in the study and were enrolled during their outpatient visit. Except for the demographic and clinical data, the variables of interest comprised of RAPID3 scores and assessments of the function of the hand, specifically, the signal of functional impairment (SOFI)-hand, grip strength and pulp-to-palm distance, plus the Health Assessment Questionnaire- Disability Index (HAQ-DI) and DAS28 scores.

Student’s t-test, linear regression and Pearson’s correlation coefficient were used to depict the statistical analysis of the outcomes. The significance was allocated as p<0.05. The values of RAPID3 scores and HAQ-DI scores, SOFI-hand scores and pulp-to-palm distance portrayed a positive correlation. As for the values of RAPID3 scores and grip strength, the negative correlation was observed. The strength of correlations between RAPID3 scores and other variables (from the strongest to the weakest) followed the order: HAQ-DI, grip strength, SOFI-hand and pulp-to-palm distance. The hand assessment variables were strongly correlated with RAPID3 scores with DAS28 scores.

This finding revealed that RAPID3 could be used as a measure of disease activity in clinical practice and to indicate hand function. Future studies are required to validate this result.


Clinical Rheumatology

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The original title of the article:

RAPID3 scores and hand outcome measurements in RA patients: a preliminary study


Merita Qorolli et al.

Diagnostic, Rheumatoid Arthritis, Joints, Preliminary Study, DAS28 Score, HAQ-DI, SOFI, RAPID3, Hand Outcome Measurements
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