Prevalence and factors associated with sarcopenia in patients with rheumatoid arthritis

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SCIENCE
Prevalence and factors associated with sarcopenia in patients with rheumatoid arthritis
Key Take-Away: 

Many patients with rheumatoid arthritis known to experience from muscular weakness, a condition of reduced muscle mass known as sarcopenia, leads to functional disability. The following study was done to evaluate the rate of RA patients suffered from sarcopenia.

Introduction
Sarcopenia is described by the muscle strength and mass loss, following falls and adverse health issues. The study intended to evaluate sarcopenia prevalence among rheumatoid arthritis (RA) patients and assess factors correlated with sarcopenia.

 

Methods
A cross-sectional analysis with 388 consecutive RA women was conducted. The assessment of bone fractures and falls maintained above the previous year was done. Logistic regression analyses were used to assess sarcopenia association with RA characteristics, falls, and bone fractures.

 

Results
The 37.1% prevalence was noticed for sarcopenia with 49.0% of low muscle mass. The RA patients with sarcopenia presented high rates of fractures, low bone mineral density and falls. The independent factors noticed to be related with sarcopenia were Steinbrocker’s stage, use of biological disease-modifying antirheumatic drugs (bDMARDs), the high Mini-Nutritional Assessment-Short Form score, age, and RA duration.

 

Conclusion
Many patients with RA known to develop sarcopenia. The bDMARDs showed negative, and other factors showed a positive relation with sarcopenia.

Source:

Modern Rheumatology

Link to the source:

https://www.tandfonline.com/doi/abs/10.1080/14397595.2018.1510565

Original title of article:

Prevalence and factors associated with sarcopenia in patients with rheumatoid arthritis

Authors:

Mie Torii et al.

Exploratory, Rheumatoid Arthritis, Joints
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