No associations found between BMD and knee cartilage defects or BMLs

Primary tabs

NEWS
No associations found between BMD and knee cartilage defects or BMLs

Osteoarthritis is the common prevalent type of arthritis. While it can appear even in young people, the chance of growing chronic breakdown of cartilage in the joints arises after the age of 45. According to the Arthritis Foundation, more than 27 million characters in the U.S. have osteoarthritis, with the knee being one of the most affected areas. Women are more likely to have osteoarthritis than men.

The connection between bone mineral density (BMD) and osteoarthritis (OA) remains controversial. Knee osteoarthritis study aimed to explore the cross-sectional relationship between BMD at the total body, hip, and spine and joint structural abnormalities along with cartilage defects and bone marrow lesions (BMLs) in patients with knee OA.
One hundred and 8-5 subjects with symptomatic knee OA were involved in this evaluation. T2-weighted fast spin echo magnetic resonance imaging was used to evaluate knee cartilage deficits and BMLs. Total body, hip, and spine BMD were estimated using dual-energy X-ray absorptiometry.

After potential confounders were adjusted, total hip BMD was negatively related to medial tibial cartilage deficits, lateral femoral cartilage deficits, medial tibial BMLs and lateral tibial BMLs. Spine and whole body BMD were negatively related to lateral femoral cartilage deficits, but not with BMLs. The evaluation achieved that BMD, particularly at the hip, was negatively associated with knee cartilage defects and BMLs. 

Source:

Int J Rheum Dis. 2017 Aug 1

Link to the source:

http://onlinelibrary.wiley.com/doi/10.1111/1756-185X.13148/abstract  

Original title of the article:

Associations between systemic bone mineral density, knee cartilage defects and bone marrow lesions in patients with knee osteoarthritis.

Authors:

Qicui Zhu et al.

SearchTags: 
Diagnostic, Osteoarthritis, Knee, Chronic, Cross-sectional, X-ray absorptiometry, BMD
Log in or register to post comments