New approach to diagnose low back pain as per Feinstein Institute clinical study
At the Feinstein Institute for Medical Research, research scientists have invented new and personalized approach to identifying lumbar intervertebral disc (low back pain). This clinical study findings are published in Arthritis Research and Therapy which reported that interleukin-6 (IL-6) is a proinflammatory cytokine differ in people with low back pain and the biochemical profiling of circulating cytokines may aid in improving personalized diagnoses of diseases of disc.
In the US, second most common cause of physician visits is low back pain. It made explicits that low back pain causes a significant burden on both the healthcare system and the economy because it is responsible for investing $100 billion costs per year. Intervertebral disc herniation, degenerative disc disease and spinal stenosis are some of the common diagnoses for low back which is caused by multiple triggers. However, physicians are trying to find out possible ways of treatments.
Feinstein Institute researchers in parternship with Northwell Health which formerly known as the North Shore-LIJ Health System and in the departments of neurosurgery and physical medicine and rehabilitation, clinicians deemed at the participant's profile of biochemical with low back pain by studying cytokines such as IL-6 to verify that how the pain levels and behaviour of these patients with LBP influenced. Age, symptom duration and body mass index are reported as well to find out that the serum levels effected or not.
Nadeen Chahine, PhD, associate investigator at the Feinstein Institute who conducted this clinical study, quoted, "We're very excited by the results of this clinical study and will continue to study cytokine levels in the future. Exploring the biochemical profile of those who suffer from low back pain will help the 40 to 80 percent of sufferers throughout the US."
A total 133 participants and control group with low back pain recruited from Northwell Health by Nadeen Chahine and her team. Results depicted that participants experienced higher serum level of IL-6 than control participants. Over and above, higher serum level also noticed in low back pain due to spinal stenosis or degenerative disc disease than intervertebral disc herniation and controls.
Hence, these clinical studies postulates that low-grade systemic inflammation found in sufferers with low back pain and biochemical profiling of circulating cytokines can help in diagnosing those with low back pain. It will assist the people with low back pain and get the proper diagnosis in a shorter period of time.