Neuromodulation in Postherpetic Neuralgia: Case Reports and Review of the Literature

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Neuromodulation in Postherpetic Neuralgia: Case Reports and Review of the Literature
Key Take-Away: 

Postherpetic neuralgia is a severe condition of pain arises amidst the nerves. This pain may affect the functioning of the nerves which can be improved by neuromodulation. This study illuminates the various methods of neuromodulation to counter neuralgia pain and suggests that peripheral nerve stimulation improved patients outcomes in postherpetic neuralgia.

Postherpetic neuralgia (PHN) is common in the United States. Current treatment options for PHN are fairly limited.

ABSTRACT: 
Background: 

Postherpetic neuralgia (PHN) is common in the United States. Current treatment options for PHN are fairly limited.

Spinal cord stimulation (SCS) and peripheral nerve stimulation (PNS) are considered mostly experimental and still rarely performed in patients with PHN. Two case reports and a review of the literature was done to evaluate neuromodulation modalities at the Tertiary academic medical center.

Methods: 

1) Pubmed, Ovid, and EBMR databases were searched for all reports that had the following keywords: postherpetic neuralgia, spinal cord stimulation, and peripheral nerve stimulation.

2) A retrospective chart review was performed for all the patients that underwent PNS for PHN at Mayo Clinic Florida (MCF).

Results: 

There were 20 original reports that described 309 patients with PHN who were treated with SCS. Sixteen reports had a permanent implantation of SCS, with a total of 255 patients, out of which 120 had long-term pain relief. There were six reports of subcutaneous PNS for PHN (in a thoracic area).

Four reports provided data on success rates where all five patients received complete pain relief. In our practice, two patients underwent subcutaneous PNS for PHN (in the thoracic area) with good pain relief for 10 months and 2.5 years, respectively.

Conclusion: 

Based on our review of the literature and the two cases at MCF, subcutaneous PNS seems to be a promising intervention in the treatment of PHN.

 

Source:

Pain Med pnx175.

Link to the source:

https://academic.oup.com/painmedicine/articleabstract/doi/10.1093/pm/pnx175/3977948/Neuromodulation-in-Postherpetic-Neuralgia-Case?redirectedFrom=fulltext

The original title of the article:

Neuromodulation in Postherpetic Neuralgia: Case Reports and Review of the Literature

Authors:

Svetlana Kurklinsky et al.

Therapeutic, Postherpetic Neuralgia, Nerves, Case Studies and Retrospective Chart Review, Subcutaneously
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