Nerve-sparing Laparoscopy Eradicates Deep Infiltrating Endometriosis

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Nerve-sparing Laparoscopy Eradicates Deep Infiltrating Endometriosis

A recent study by Stefano Uccella and colleagues demonstrated a significant role of nerve-sparing intervention in eradicating deep infiltrating endometriosis (DIE) of the posterior compartment, with adequate pain control, considerable improvement of sexual function, and preservation of bladder and rectal function.

Approaches like radical eradication of DIE has been found to be linked with a high risk of iatrogenic autonomic denervation and pelvic dysfunction. The present study was conducted to determine nerve-sparing peri-operative features and postoperative functional results related to rectal, sexual, bladder functioning and pain reduction in patients with DIE.

The females with DIE nodules of the posterior compartment ≥ 4 cm ± bowel resection who were going through laparoscopic nerve-sparing eradication surgery were selected for the analysis. Visual Analogue Scale (VAS) was used to collect pain scores before and 6 & 12 months after the surgery. The NBD, ICIQ-UISF and FSFI questionnaires were used to determine rectal, bladder and sexual functions before and six months after the treatment.

The analysis involved 34 patients; out of which 28 patients already went through a previous abdominal surgery and the remaining 16 patients were subjected to bowel resection. There was a considerable reduction in the pelvic pain scores at six months and one year after surgery. ICIQ-SF questionnaires showed no difference between pre- and post-operative urinary functioning. NBD scores reduced from 3.5 to 2 at six months after the treatment (p = 0.72). No self-catheterization of the bladder was required at six month and one-year follow-up. The total FSFI scores shifted to 22.7 from 19.1 after the treatment.


Archives of Gynecology and Obstetrics             

Link to the Source:

The original title of the article:

Functional outcomes of nerve-sparing laparoscopic eradication of deep infiltrating endometriosis: a prospective analysis using validated questionnaires


Stefano Uccella et al.

Therapeutic, Endometriosis, Uterus, Prospective Analysis, Efficacy, VAS, NBD, ICIQ-UISF, FSFI
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