Hippocampal Volume and Alcohol Consumption Association in Fibromyalgia and Insomnia

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Hippocampal Volume and Alcohol Consumption Association in Fibromyalgia and Insomnia

A lot of people with fibromyalgia also have a sleep disorder called as insomnia. If insomnia is detected early, it would be easy to reduce the risk of fibromyalgia and other chronic illnesses. People with fibromyalgia commonly take supplements that improve sleep, such as melatonin and valerian.

However, it is believed that alcohol consumption can be helpful in treating the pain associated with fibromyalgia and also insomnia. Fibromyalgia and chronic insomnia are frequently co-morbid conditions with heightened sensitivity to painful stimuli potentially sub served by the hippocampus. It was noted that in 41 fibromyalgia patients, recent evidence suggested the moderate alcohol consumption was associated with reduced fibromyalgia symptom severity. A 14-day diary of sleep, pain and alcohol consumption which was followed by structural MRI.

After the analysis, result indicated the greater bilateral hippocampal volume with lower clinical pain intensity and better sleep quality in moderate drinkers versus abstainers. Underlying mechanism may include gamma-amino butyric acid (GABA) receptor agonism, n-methyl d-aspartate (NMDA) receptor antagonism and psychosocial factors. But, further study is still needed of the relationship between alcohol use and fibromyalgia and insomnia symptom severity is warranted.

Behav Sleep Med.
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