Dextrose prolotherapy can significantly reduce the mouth opening and pain associated with TMJ hypermobility

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Dextrose prolotherapy can significantly reduce the mouth opening and pain associated with TMJ hypermobility

A recently published study in the 'Journal of Oral Rehabilitation' highlighted that dextrose prolotherapy might lead to a significant reduction in mouth opening and pain related to TMJ hypermobility. 
The systematic review was carried out to examine the available evidence investigating the efficacy of dextrose prolotherapy in refining the outcomes in temporomandibular joint (TMJ) hypermobility patients as compared to placebo.

 The PubMed, Scopus, CENTRAL and Google scholar were extensively searched for English language research papers published up to February 2018. The randomised clinical trials (RCTs) and controlled clinical trials (CCTs) comparing dextrose prolotherapy with placebo for TMJ hypermobility were considered.
In the review, 3 RCTs were considered. In 2 trials, the frequency of subluxation/dislocation was reported which found no difference between dextrose and placebo. When the data were pooled, a statistically significant difference in reduction of MMO with the use of dextrose prolotherapy was observed. In comparison with placebo, dextrose displayed a statistically significant difference in pain reduction. 
All in all, the conclusions with respect to the reduction of episodes of subluxation/dislocation cannot be drawn. Moreover, high-quality RCTs along with larger sample size and homogenous prolotherapy protocol to draw stronger conclusions on the effect of dextrose prolotherapy in TMJ hypermobility patients are required for further analyses and findings.   

Source

J Oral Rehabil. 2018 Jul 19.

Link to the source

https://www.ncbi.nlm.nih.gov/pubmed/30024045

Original title of the article

The efficacy of dextrose prolotherapy over placebo for temporomandibular joint hypermobility: a systematic review and meta-analysis

Authors

Nagori SA et al.

SearchTags: 
Therapeutic, Dextrose, Pain, Joint hypermobility, Temporomandibular joint, Systematic
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