Clinical Recommendations for Rational Use of NSAIDs in Russia
NSAIDs display anti-inflammatory, anaesthetic and antipyretic effects and indicated for the relief of acute and chronic pain in a wide variety of clinical disorders. They act via blockade of pro-inflammatory enzyme cyclooxygenase
(COX) and the decrease of prostaglandin levels. NSAIDs are prescribed extensively by therapists, rheumatologists, neurologists, anesthesiologists, surgeons, traumatologists, gynaecologists, etc.