Clinical periodontal attachment has a link with BMD in postmenopausal women

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Clinical periodontal attachment has a link with BMD in postmenopausal women

Osteoporosis is a systemic skeletal disease associated with low bone mineral density (BMD) and has been regarded as a risk factor for periodontal disease. The scientific evidence for the association between periodontal attachment loss and low BMD in postmenopausal women was evaluated by Penoni DC and colleagues through a systematic review and meta-analysis.

Until August 2016, a systematic search of the literature was executed concerning Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines.Studies comparing clinical attachment loss (CAL) between postmenopausal women with low and normal BMD were included in the study. Studies using the similar methodology, with lower and higher risk of bias, were pooled into 3 distinct meta-analyses to differentiate CAL among women with normal BMD, osteoporosis, and osteopenia.

To distinguish CAL among women with normal BMD, osteoporosis, and osteopenia, the study with similar methodology having lower and higher risk of bias were pooled into 3 distinct meta-analyses. The mean CAL was distinguished among groups in the first meta-analysis. The mean percentages of sites with CAL ≥4 mm and ≥6 mm were respectively distinguished among groups in the other 2 meta-analyses.

A total of 26 articles were picked for the qualitative synthesis from 792 unique citations. Eleven studies portrayed as low risk of bias, and in ten of these studies, the alliance between low BMD and CAL was observed. The meta-analysis for osteoporosis included 13 cross-sectional articles and 9 the osteopenia analysis. A greater mean CAL than those with normal BMD (osteoporosis = 0.34 mm [95% confidence interval (CI), 0.20–0.49], p<0.001; osteopenia = 0.07 mm [95% CI, 0.01–0.13], p=0.02) was observed in women with low BMD. The analysis of CAL severity inculcated only the studies with lower risk of bias. More severe attachment loss was observed in women with low BMD, depicted as mean percentage of sites with CAL ≥4 mm (osteoporosis = 3.04 [95% CI, 1.23–4.85], p=0.001; osteopenia = 1.74 [95% CI, 0.36–3.12], p=0.01) and CAL ≥6 mm (osteoporosis = 5.07 [95% CI, 2.74–7.40], p<0.001).

Thus, it can be concluded that the postmenopausal women with osteoporosis or osteopenia may present greater CAL compared with women with normal BMD.  

Source:

Journal of dental research

Link to the source:

http://journals.sagepub.com/doi/abs/10.1177/0022034516682017?url_ver=Z39.882003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed&

Original title of article:

Bone Density and Clinical Periodontal Attachment in Po stmenopausal Women: A Systematic Review and Meta-Analysis

Authors

D.C. Penoni et al.

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