Chronic Prostatitis/Chronic Pelvic Pain as a Psycho-Neuromuscular Disorder-A Meta-analysis

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Chronic Prostatitis/Chronic Pelvic Pain as a Psycho-Neuromuscular Disorder-A Meta-analysis
Key Take-Away: 

Chronic Prostatitis/Chronic Pelvic Pain accounts for the most prevalent cases which involved severe pelvic pain. Since the traditional therapies often fail to understand CP/CPPS condition, this study characterizes CP/CPPS disease as a Psycho-Neuromuscular Disorder to explores suitable treatment approaches which can resolve the problem and improve related manifestations.

To assess the efficacy of cognitive behavioural therapy, biofeedback and/ or physical therapy for chronic prostatitis/chronic pelvic pain syndrome (cp/cpps). This symptom complex has combated resolution from the conventional urologic treatment of the prostate, which involves physical therapy, alpha-blockers and antibiotics. The latest paradigm was incorporated in the Beginning 1995 that observing CP/CPPS as a psycho-neuromuscular disorder induced by psychosocial stress and protective pelvic floor guarding.


The google scholar, the Cochrane Library and PubMed were analysed from inception through December 2017 to search literature. Keywords used during the search were CP/CPPS (e.g., prostatitis, pelvic pain) with biofeedback, cognitive behavioural treatment and physical therapy (e.g., myofascial trigger point release). The studies involved pre and post-treatment with the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) scores were included.


A total of eight studies including 280 patients matched the primary inclusion criteria. Study sample masses covered from 8 to 116 men (mean = 35) and treatment duration varied from 8 to 26 weeks (mean = 14). The pre-treatment mean CPSI scores were ranged from 21.7 to 33.5. An 8.8 points reduction in non-standardised weighted mean CPSI score from the baseline was noticed ( p<0.001). A little heterogeneity (18.5%) between the studies were seen via I2 statistic. The sensitivity analysis with an additional multimodal approach study (100 patients) displayed similar findings.


Traditional medical treatment often fails to resolve cp/cpps. A 6-point reduction in CPSI score is regarded as a clinically significant symptoms improvement. This meta-analysis explains that handling CP/CPPS as a psycho-neuromuscular disorder can significantly beat this clinical threshold.



Link to the source:

Original title of article:

Chronic Prostatitis/Chronic Pelvic Pain as a Psycho-Neuromuscular Disorder-A Meta-analysis


Rodney U. Anderson et al.

Exploratory, Prostatitis, Prostate, Meta-analysis, CPSI scores
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