The unloading knee brace treatment found effective in patients with symptomatic knee osteoarthritis

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The unloading knee brace treatment found effective in patients with symptomatic knee osteoarthritis

A recent study conducted in France by nine private and one hospital-based physician highlighted the significance of a novel unloading brace treatment in managing symptomatic knee osteoarthritis. Unloading knee braces provide extraordinary relief from arthritis pain. However, evidence regarding its efficacy is still indefinite.

This study was conducted to determine more evidence concern with knee braces effectiveness. The study is a randomized, prospective, multicenter, controlled, two-arm, parallel-group, open-label, Phase III trial which involved 67 patients having symptomatic knee osteoarthritis. Out of these, 32 patients placed in the brace group who received usual care with unloading knee brace treatment. The other group is the control group, received only usual care. The global last 24h-pain relief at 6 weeks was considered as primary endpoint and function, safety, pain on motion and observance was taken as secondary endpoints. The visual analogic scale (VAS) was used to measure pain and Lequesne index to measured function.
The brace group exhibited a significant reduction in mean last 24h-pain, pain on motion and better Lequesne index score as compared to the control group at 6 weeks. The observance and safety were also better among brace group. These results indicated that this new unloading braces provide a significant reduction in pain related to knee osteoarthritis.


Sci Rep.  


The original title of article:

Effect of unloading brace treatment on pain and function in patients with symptomatic knee osteoarthritis: the ROTOR randomized clinical trial


Philippe Thoumie et al.

Therapeutic, Knee Osteoarthritis, Joints, Knee, Randomized, Prospective, Multicenter, Controlled, Two-arm, Parallel-group, Open-label, Phase III Trial, Efficacy, Safety, VAS, Lequesne Index
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