Safety and efficacy of US-approved viscosupplements for knee osteoarthritis: a systematic review and meta-analysis of randomized, saline-controlled trials
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SCIENCE
Safety and efficacy of US-approved viscosupplements for knee osteoarthritis: a systematic review and meta-analysis of randomized, saline-controlled trials
Key Take-Away:
Hyaluronic acid (HA) is an important part of synovial fluid that acts as joint lubricant during shear stress and shock absorber during compressive stress. According to this study, this US-approved viscosupplements for knee osteoarthritis was proved to be beneficial.
Intra-articular injection of hyaluronic acid is a common, yet controversial, therapeutic option for patients with knee osteoarthritis (OA).
ABSTRACT:
Background:
Methods:
Results:
Conclusion:
Intra-articular injection of US-approved viscosupplements is safe and efficacious through 26 weeks in patients with symptomatic knee OA.
J Pain Res. 2015 May 7;8:217-28