Novel therapeutic intervention in diabetic peripheral neuropathy

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Novel therapeutic intervention in diabetic peripheral neuropathy

Peripheral neuropathy is nerve damage caused by chronically high blood sugar and diabetes. It leads to numbness, loss of sensation and sometimes pain in feet, legs or hands. It is the most common complication of diabetes. Diabetic peripheral neuropathy increases the risk for foot ulcers and amputation. Aside from strict glycemic control, no further remedial methodology exists in the prevention of this phenomenon.

The reasons that just a few patients with nerve lesions develop neuropathic torment are still obscure. Various therapies have also been developed to cure the diabetic neuropathy. Nowadays, new intervention techniques have also been developed.

In order to determine the effect of a novel therapeutic intervention called intraneural facilitation on balance measures and to calculate the neuropathy scale in patients with diabetic peripheral neuropathy, a trial was conducted.

Thirteen patients with diabetic peripheral neuropathy was given 10 sessions of intraneural facilitation. Outcome measures was calculated by the modified Total Neuropathy Scale, the NeuroCom SMART Balance Master system computerized dynamic posturography (CDP) that included the Sensory Organization Test (SOT), the limits of stability (LOS) and the Activities-specific Balance and Confidence (ABC) scale. After finishing the study, patients showed significant improvement in the modified Total Neuropathy Scale and 1 component in the LOS test. No significant differences in the ABC scale or in 4 components of the LOS test were observed, which were reaction time, end point excursion, maximum excursion and directional control.

After analysis of statistical results, it has been proven that Intraneural facilitation showed the improved objective balance measures and neuropathy symptoms in patients with diabetic peripheral neuropathy. However, further study is still needed to determine the long-term benefits of this intervention.

Archives of physical medicine and rehabilitation
Therapeutic, Diabetic Peripheral Neuropathy, Nerves, Prospective pre- and posttest, Single Group Clinical Trial, Modified Total Neuropathy Scale
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