Chronic Migraine Epidemiology and Outcomes assessed for Comorbid pain and migraine chronicity

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Chronic Migraine Epidemiology and Outcomes assessed for Comorbid pain and migraine chronicity

A migraine is a painful neurovascular disorder with an estimated prevalence of ≈15%. Current diagnostic criteria divide a headache into episodic (EM; <15 headache-days per month) and chronic (CM; ≥15 headache-days per month for >3 months among migraine characteristic. A migraine is comorbid among a large number of pain disorders.

Recognise the patterns of noncephalic pain comorbidity in people with episodic migraine (EM; <15 headache-days per month) including a chronic migraine (CM; ≥15 headache-days per month) and to analyse whether noncephalic pain could be an indicator for the 3-month onset or persistence of CM. From the Chronic Migraine Epidemiology and Outcomes (CaMEO) Study, which was a prospective, web-based study with cross-sectional modules embedded in a longitudinal design, the data were evaluated, at baseline and the 3-month follow-up. Relationships were studied between the number of noncephalic pain sites and the 3-month onset of CM or persistent CM.

Of 8,908 desirable respondents, 8,139 (91.4%) had EM and 769 (8.6%) had CM at baseline. At three months, the incidence of CM among those with baseline EM was 3.4%. When regulated for demographics and headache-day frequency, the odds of CM onset among those with baseline EM grow by 30% (95% confidence interval [CI] 1.21–1.40, p < 0.001) for each auxiliary on cephalic pain site at baseline. Amid those with CM at baseline, 50.1% had persistent CM at the 3-month follow-up. After reconciliation for demographics, each with CM was 15% (95% CI 1.07–1.25, p < 0.001) more probable to have persistent CM for individual auxiliary noncephalic pain site at baseline.

The assessment recommended that noncephalic pain may be a marker for headache chronicity that could be utilised to identify people with EM at risk of the onset of CM and people with CM at risk of persistent CM.


Neurology. 2017 Aug 1;89(5):461-468

Link to the source:

Original title of the article:

Comorbid pain and migraine chronicity: The Chronic Migraine Epidemiology and Outcomes Study.


Ann; I. S. et al.

Diagnostic, Pain, Migraine, Chronic, CaMEO, Prospective, Cross-sectional
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