Cardiovascular risk management for gout and rheumatoid arthritis
Cardiovascular risks are associated with the heart conditions that include diseased vessels, structural problems and blood clots. In a primary care retrospective cohort study employed in the Dutch primary care population, gout and rheumatoid arthritis patients were considered for the study of cardiovascular perils efficiently.
About 51 Dutch general practices comprising participants of age 30 years or older with an incident diagnosis of gout (n = 2655) or rheumatoid arthritis (n = 513), and matched non-disease controls (n = 7891 and n = 1850 respectively). These patients were distinguished for generality of diabetes mellitus, hypertension, hypercholesterolemia, and prior cardiovascular diseases. The patients without prior cardiovascular disease were followed for an initial cardiovascular disease and compared to controls using Kaplan-Meier survival curves and Cox proportional hazard analyses.
Varied outcomes resulted from the study showing high ratios of cardiovascular risks for gout (hypertension-44.8%, diabetes- 20.1%, hypercholesterolemia -13.7% with P < 0.01) as compared to rheumatoid arthritis (hypertension - 28.5%, diabetes - 11.7%, hypercholesterolemia - 7.4% with P < 0.01) patients. Also, the gout and rheumatoid arthritis patients without prior cardiovascular disease after adjustment were more likely to get a cardiovascular disease: hazard ratio (95% confidence interval) 1.44 (1.18 to 1.76), and 2.06 (1.34 to 3.16). This study gave powerful arguments for implementation of both rheumatic diseases in primary care guidelines on cardiovascular risk management.